Evidence map›Paper›PMID 38164360›Full record

ArticleInternational journal of medical sciences2024

Inhibition of Polyinosinic-Polycytidylic Acid-Induced Acute Pulmonary Inflammation and NF-κB Activation in Mice by a Banana Plant Extract.

Chien-Huang Liao, Tung-Yuan Lai, Yu-Ying Lin, Yi-Chun Liao, Gi-Ming Lai, Tien-Hua Chu, Szu-Yao Wu, Wei-Lun Tsai, Jacqueline Whang-Peng, Frank Liu and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Chien-Huang LiaoCancer Center, Wan Fang Hospital, Taipei Medical University, Taipei 11696, Taiwan.
Tung-Yuan LaiDepartment of Chinese Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 97002, Taiwan.
Yu-Ying LinCancer Center, Wan Fang Hospital, Taipei Medical University, Taipei 11696, Taiwan.
Yi-Chun LiaoInstitute of Biomedical Sciences, Academia Sinica, Taipei, 11529, Taiwan.
Gi-Ming LaiCancer Center, Wan Fang Hospital, Taipei Medical University, Taipei 11696, Taiwan.
Tien-Hua ChuChimera Bioscience Inc., No. 18 Siyuan St., Zhongzheng Dist., Taipei 10087, Taiwan.
Szu-Yao WuChimera Bioscience Inc., No. 18 Siyuan St., Zhongzheng Dist., Taipei 10087, Taiwan.
Wei-Lun TsaiCancer Center, Wan Fang Hospital, Taipei Medical University, Taipei 11696, Taiwan.
Jacqueline Whang-PengCancer Center, Wan Fang Hospital, Taipei Medical University, Taipei 11696, Taiwan.
Frank LiuDepartment of Research and Development, Natural Well Technical Company, Guishan, Taoyuan 33377, Taiwan.
Tzeon-Jye ChiouCancer Center, Wan Fang Hospital, Taipei Medical University, Taipei 11696, Taiwan.
Chih-Jung YaoDepartment of Medical Education and Research, Wan Fang Hospital, Taipei Medical University, Taipei 11696, Taiwan.
Wan Fang Hospital · TWNational Taipei University of Education · TWTaipei Medical University · TWHualien Tzu Chi Medical Center · TWInstitute of Biomedical Sciences, Academia Sinica · TWNational Taiwan Sport University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NF-κB activation is pivotal for the excess inflammation causing the critical condition and mortality of respiratory viral infection patients. This study was aimed to evaluate the effect of a banana plant extract (BPE) on suppressing NF-κB activity and acute lung inflammatory responses in mice induced by a synthetic double-stranded RNA viral mimetic, polyinosinic-polycytidylic acid (poly (I:C)). The inflammatory responses were analyzed by immunohistochemistry and HE stains and ELISA. The NF-κB activities were detected by immunohistochemistry

Indexed as

MusaPneumoniaAnimalsAnti-Inflammatory AgentsChemokinesCytokinesHumansInflammationInterleukin-10Interleukin-6MiceNF-kappa BPlant ExtractsPoly I-CAnti-Inflammatory AgentsChemokinesCytokinesInterleukin-10Interleukin-6NF-kappa BPlant ExtractsPoly I-Cacute pulmonary inflammationbanana plant extractIL-6NF-κB

Identifiers

PMID38164360
PMCPMC10750330
OpenAlexW4388699688

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.