Evidence map›Paper›PMID 38164403›Full record

ReviewFrontiers in bioengineering and biotechnology2023

Graphene-based nanomaterials for peripheral nerve regeneration.

Domenica Convertino, Maria Letizia Trincavelli, Chiara Giacomelli, Laura Marchetti, Camilla Coletti

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Special Issue: "Application of Nanotechnology in Regenerative Medicine".International journal of molecular sciences · 2025
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  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
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  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Domenica ConvertinoCenter for Nanotechnology Innovation @NEST, Istituto Italiano di Tecnologia, Pisa, Italy.
Maria Letizia TrincavelliDepartment of Pharmacy, University of Pisa, Pisa, Italy.
Chiara GiacomelliDepartment of Pharmacy, University of Pisa, Pisa, Italy.
Laura MarchettiCenter for Nanotechnology Innovation @NEST, Istituto Italiano di Tecnologia, Pisa, Italy.
Camilla ColettiCenter for Nanotechnology Innovation @NEST, Istituto Italiano di Tecnologia, Pisa, Italy.
Italian Institute of Technology · ITUniversity of Pisa · ITCenter for Nanotechnology Innovation · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging nanotechnologies offer numerous opportunities in the field of regenerative medicine and have been widely explored to design novel scaffolds for the regeneration and stimulation of nerve tissue. In this review, we focus on peripheral nerve regeneration. First, we introduce the biomedical problem and the present status of nerve conduits that can be used to guide, fasten and enhance regeneration. Then, we thoroughly discuss graphene as an emerging candidate in nerve tissue engineering, in light of its chemical, tribological and electrical properties. We introduce the graphene forms commonly used as neural interfaces, briefly review their applications, and discuss their potential toxicity. We then focus on the adoption of graphene in peripheral nervous system applications, a research field that has gained in the last years ever-increasing attention. We discuss the potential integration of graphene in guidance conduits, and critically review graphene interaction not only with peripheral neurons, but also with non-neural cells involved in nerve regeneration; indeed, the latter have recently emerged as central players in modulating the immune and inflammatory response and accelerating the growth of new tissue.

Indexed as

CVD graphenegraphene-based materialsgraphene-based neural interfacesnerve conduitsperipheral nerve regeneration

Identifiers

PMID38164403
PMCPMC10757979
OpenAlexW4389915716

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.