Evidence map›Paper›PMID 38167532›Full record

ArticleArthritis research & therapy2024

Proteomic profiling identifies SPP1 associated with rapidly progressive interstitial lung disease in anti-MDA5-positive dermatomyositis.

Yulu Qiu, Xiaoke Feng, Chang Liu, Yumeng Shi, Lingxiao Xu, Hanxiao You, Lei Wang, Chengyin Lv, Fang Wang, Wenfeng Tan

Open access · goldAbstract read
In one paragraph

Article in Arthritis research & therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Epidemiology of myositis.Current opinion in rheumatology · 2025
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yulu Qiu *Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu Province, China.
Xiaoke Feng *Department of Traditional Chinese Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Chang LiuDepartment of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu Province, China.
Yumeng ShiDepartment of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu Province, China.
Lingxiao XuDepartment of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu Province, China.
Hanxiao YouDepartment of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu Province, China.
Lei WangDepartment of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu Province, China.
Chengyin LvDepartment of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu Province, China.
Fang WangDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu Province, China. wangfangheart@njmu.edu.cn.
Wenfeng TanDepartment of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu Province, China. tw2006@njmu.edu.cn.ORCID 0000-0002-5160-2023
Jiangsu Province Hospital · CNNanjing University of Chinese Medicine · CN

Funding

National Natural Science Foundation 81971533National Natural Science Foundation 82171794National Natural Science Foundation 82271844National Natural Science Foundation 82302041
6 · The paper itself

Abstract

backgroundAnti-melanoma differentiation-associated gene five antibody positive (MDA5

methodsPlasma samples from 20 MDA5

resultsA total of 413 differentially expressed proteins (DEPs) were detected between the MDA5

conclusionThis study provides novel insights into the pathogenesis of RP-ILD development in MDA5

Indexed as

DermatomyositisLung Diseases, InterstitialAutoantibodiesBiomarkersChromatography, LiquidDisease ProgressionHumansInterferon-Induced Helicase, IFIH1OsteopontinPrognosisProteomicsRetrospective StudiesTandem Mass SpectrometryAutoantibodiesBiomarkersInterferon-Induced Helicase, IFIH1OsteopontinSPP1 protein, humanBiomarkerDermatomyositisInterstitial lung diseaseMDA5RP-ILD

Identifiers

PMID38167532
PMCPMC10759429
OpenAlexW4390508877

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.