Evidence map›Paper›PMID 38168334›Full record

ArticlebioRxiv : the preprint server for biology2023

Boosting bactericidal immunity of a recombinant

Shivani Singh, David Kanzin, Sarah Chavez, N Alejandra Saavedra-Avila, Tony W Ng, Regy Lukose, Oren Mayer, John Kim, Bing Chen, Mei Chen and 3 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Shivani Singh
David Kanzin
Sarah Chavez
N Alejandra Saavedra-Avila
Tony W Ng
Regy Lukose
Oren Mayer
John Kim
Bing Chen
Mei Chen
Steven A Porcelli
William R Jacobs

Funding

Development of Drugs to Target Arginine Biosythesis in Mycobacterium tuberculosisSC1GM140968 · NIGMS · UNIVERSITY OF TEXAS EL PASO · PI TIWARI, SANGEETA · 2021 to 2024
$1.5M
NIGMS NIH HHS SC1 GM140968
6 · The paper itself

Abstract

Tuberculosis (TB) continues to be a major global health burden and kills over a million people annually. New immunization strategies are required for the development of an efficacious TB vaccine that can potentially induce sterilizing immunity. In this study, we first confirmed that various strains of the IKEPLUS vaccine confer a higher survival benefit than BCG in a murine model of intravenous

Identifiers

PMID38168334
PMCPMC10760040

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.