ArticleMicrosystems & nanoengineering2024
Enhancing single-cell encapsulation in droplet microfluidics with fine-tunable on-chip sample enrichment.
Article in Microsystems & nanoengineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Review
- Decoding Cellular Heterogeneity with Microfluidic Single-Cell Secretion Analysis Tools.ACS omega · 2026Review
- On-Demand Viscosity Gradients Turn Nanoliter Droplets into Programmable Sources of Enriched Picoliter Droplets.Journal of the American Chemical Society · 2026Article
- CellTrap: an instrument-free microfluidic platform for cell-cell interactions at stochastically generated effector-to-target ratios.RSC advances · 2026Article
- Capillary microfluidics aided single-cell manipulation for optical detection of bacterial pathogens.Biophysical reviews · 2026Review
- A high-precision nanoliter droplet dispensing system based on optoelectrowetting with tunable droplet volume.Microsystems & nanoengineering · 2025Article
- A single-cell digital PCR method tailored for quantification of HBV DNA positive cells in liver biopsy tissues.Journal of translational medicine · 2025Article
- Hydrogel Microspheres as Versatile Platforms for Biomedical Research: Design, Properties, and Applications.MedComm · 2025Review
- Hydrogel particle-based protein display enabled by particle-templated emulsification.RSC advances · 2025Article
- Droplet-based bioprinting.Nature reviews. Methods primers · 2025Article
- Innovative Advances in Droplet Microfluidics.Research (Washington, D.C.) · 2025Review
- A simple guideline for designing droplet microfluidic chips to achieve an improved single (bio)particle encapsulation rate using a stratified flow-assisted particle ordering method.Biomicrofluidics · 2024Article
- Droplet Microfluidics for High-Throughput Screening and Directed Evolution of Biomolecules.Micromachines · 2024Review
- DropBlot: single-cell western blotting of chemically fixed cancer cells.Nature communications · 2024Article
- Unveiling the Potential of Single-Cell Encapsulation in Biomedical Applications: Current Advances and Future Perspectives.Small science · 2024Article
- The use of droplet-based microfluidic technologies for accelerated selection ofBiology methods & protocols · 2024Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Single-cell encapsulation in droplet microfluidics is commonly hindered by the tradeoff between cell suspension density and on-chip focusing performance. In this study, we introduce a novel droplet microfluidic chip to overcome this challenge. The chip comprises a double spiral focusing unit, a flow resistance-based sample enrichment module with fine-tunable outlets, and a crossflow droplet generation unit. Utilizing a low-density cell/bead suspension (2 × 10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.