Evidence mapPaperPMID 38170773Full record

ArticleScience advances2024

TBscreen: A passive cough classifier for tuberculosis screening with a controlled dataset.

Manuja Sharma, Videlis Nduba, Lilian N Njagi, Wilfred Murithi, Zipporah Mwongera, Thomas R Hawn, Shwetak N Patel, David J Horne

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07018076 (Candidate Clinical Correlate of Prognostic Outcome for TB Study), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07018076 recruitingnot on this mapstarted 2025, after this paper: background citation

Candidate Clinical Correlate of Prognostic Outcome for TB Study

TypeobservationalSponsorUniversity of California, San FranciscoRan2025 to 2027Enrolled750ConditionsTuberculosisArmsRS ratio, Blood-based host immune response assays
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Cough biomarkers for diagnosis and monitoring of respiratory disease: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Manuja SharmaDepartment of Electrical and Computer Engineering, University of Washington, 185 E Stevens Way NE, Seattle, WA 98195, USA.ORCID 0000-0003-4404-7778
Videlis NdubaCentre for Respiratory Diseases Research, Kenya Medical Research Institute, Mbagathi Rd, Nairobi 610101, Kenya.
Lilian N NjagiCentre for Respiratory Diseases Research, Kenya Medical Research Institute, Mbagathi Rd, Nairobi 610101, Kenya.
Wilfred MurithiCentre for Respiratory Diseases Research, Kenya Medical Research Institute, Mbagathi Rd, Nairobi 610101, Kenya.
Zipporah MwongeraCentre for Respiratory Diseases Research, Kenya Medical Research Institute, Mbagathi Rd, Nairobi 610101, Kenya.
Thomas R HawnDepartment of Medicine, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA.ORCID 0000-0003-2368-3185
Shwetak N PatelDepartment of Electrical and Computer Engineering, University of Washington, 185 E Stevens Way NE, Seattle, WA 98195, USA.ORCID 0000-0002-6300-4389
David J HorneDepartment of Medicine, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA.ORCID 0000-0002-4721-9099
Kenya Medical Research Institute · KEUniversity of Washington · US

Funding

Institute of Translational Health SciencesUL1TR002319 · UNIVERSITY OF WASHINGTON · 2025 to 2025
$10.2M
Tuberculosis & HIV Co-Infection Training Program in KenyaD43TW011817 · UNIVERSITY OF WASHINGTON · 2025 to 2025
$287k
Pulmonary Innate Immunity & Resistance to Mycobacterium Tuberculosis InfectionK24AI137310 · NIAID · UNIVERSITY OF WASHINGTON · PI Thomas R Hawn · 2022 to 2022
$176k
FIC NIH HHS D43 TW011817NCATS NIH HHS UL1 TR002319NIAID NIH HHS K24 AI137310NIAID NIH HHS R01 AI150815NIAID NIH HHS UH2 AI152621
6 · The paper itself

Abstract

Recent respiratory disease screening studies suggest promising performance of cough classifiers, but potential biases in model training and dataset quality preclude robust conclusions. To examine tuberculosis (TB) cough diagnostic features, we enrolled subjects with pulmonary TB (

Indexed as

TuberculosisTuberculosis, PulmonaryCoughHumansKenyaROC Curve

Identifiers

PMID38170773
PMCPMC10776005
OpenAlexW4390569768

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.