Evidence map›Paper›PMID 38173204›Full record

Trial reportCurrent pediatric reviews2024

The Effectiveness of Perinatal Omega-3 Supplements in Neurodevelopment and Physical Growth of 9- and 12-month-old Infants: A Follow-up of a Clinical Trial.

Somayyeh Sarrafi, Samira Pourzeinali, Seyed Kazem Shakouri, Azizeh Farshbaf-Khalili, Alireza Ostadrahimi

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Current pediatric reviews, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Somayyeh SarrafiMidwifery Department, Bonab Branch, Islamic Azad University, Bonab, Iran.ORCID 0000-0001-5008-4191
Samira PourzeinaliAmiralmomenin Hospital of Charoimagh, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID 0000-0002-8047-5887
Seyed Kazem ShakouriPhysical Medicine and Rehabilitation Research Center, Aging Institute, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID 0000-0003-3815-4091
Azizeh Farshbaf-KhaliliPhysical Medicine and Rehabilitation Research Center, Aging Institute, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID 0000-0001-5754-4613
Alireza OstadrahimiNutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID 0000-0002-1058-1481

Funding

Tabriz University of Medical Sciences 59778
6 · The paper itself

Abstract

backgroundOmega-3 fatty acids (FAs) are essential long-chain polyunsaturated fatty acids (LCPUFAs) that are essential for optimal health and development.

objectiveThe present study aimed to evaluate the effectiveness of maternal fish oil (containing omega-3 LCPUFA) intake from 21th week of pregnancy to 30 days postpartum for neurodevelopment and growth of infants at 9 and 12 months.

methodsThis was a follow-up study of a triple-blinded clinical trial. The study population was 9- month-old infants. Their mothers were randomly divided into two groups of 75 people with a 1:1 ratio to take one fish oil supplement or a placebo daily. The anthropometric indicators of infants at months 9 and 12 and neurodevelopment at month 12 by the ASQ questionnaire were measured. In the fish oil and placebo groups, respectively, 73 and 71 infants at nine months, as well as 71 and 69 at 12 months, were analyzed.

resultsNo statistically significant impact was observed following consuming omega-3 capsules on the neurodevelopmental domains, growth parameters, and the profile of maternal serum FAs (p > 0.05) except DHA. Neurodevelopmental problems were illustrated in one case in the intervention group and two cases in the placebo group.

conclusionPerinatal relatively low-dose omega-3 LCPUFAs supplements indicated no statistically significant impacts on the growth and neurodevelopment of 9- and 12-month-old infants in a population with low consumption of marine products. Further studies investigating the effect of higher doses of omega-3 LCPUFAs are suggested.

Indexed as

Child DevelopmentDietary SupplementsFatty Acids, Omega-3AdultFemaleFish OilsFollow-Up StudiesHumansInfantMalePregnancyFatty Acids, Omega-3Fish OilsDocosahexaenoic acideicosapentaenoic acidfuture generation.health carepregnancy outcomessupplementation

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.