Evidence map›Paper›PMID 38176412›Full record

ReviewCell metabolism2024

Time-restricted eating: Watching the clock to treat obesity.

Mark Ezpeleta, Sofia Cienfuegos, Shuhao Lin, Vasiliki Pavlou, Kelsey Gabel, Lisa Tussing-Humphreys, Krista A Varady

Abstract readReview
In one paragraph

Review in Cell metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mark EzpeletaDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA.
Sofia CienfuegosDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA.
Shuhao LinDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA.
Vasiliki PavlouDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA.
Kelsey GabelDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA; University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, IL, USA.
Lisa Tussing-HumphreysDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA; University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, IL, USA.
Krista A VaradyDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA; University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, IL, USA. Electronic address: varady@uic.edu.

Funding

Mediating Role of Gut Microbiota in the Regulation of Colorectal Cancer Risk in the Context of Time-restricted Eating and Calorie RestrictionR01CA257807 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Lisa Tussing-Humphreys, Krista Amy Varady · 2021 to 2026
$5.4M
Time restricted feeding versus daily calorie restriction: Effect on body weight, metabolic risk, and the gut microbiomeR01DK128180 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI VARADY, KRISTA AMY · 2021 to 2025
$3.0M
UIC Building Interdisciplinary Research Careers in Women's Health ProgramK12HD101373 · NICHD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BUHIMSCHI, IRINA A, MAKI, PAULINE M · 2020 to 2023
$2.9M
Research Training Program in Metabolism, Obesity and Type 2 DiabetesT32DK120521 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI DANIEL Holland BESSESEN · 2020 to 2026
$2.1M
Alternate day fasting combined with exercise for the treatment of NAFLDR01DK119783 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI VARADY, KRISTA AMY · 2019 to 2022
$1.4M
NCI NIH HHS R01 CA257807NICHD NIH HHS K12 HD101373NIDDK NIH HHS R01 DK119783NIDDK NIH HHS R01 DK128180NIDDK NIH HHS T32 DK120521
6 · The paper itself

Abstract

Time-restricted eating (TRE) has become a popular strategy to treat obesity. TRE involves confining the eating window to 4-10 h per day and fasting for the remaining hours (14-20 h fast). During the eating window, individuals are not required to monitor food intake. The sudden rise in popularity of TRE is most likely due to its simplicity and the fact that it does not require individuals to count calories to lose weight. This feature of TRE may appeal to certain individuals with obesity, and this could help produce lasting metabolic health improvements. The purpose of this review is to summarize current evidence from randomized clinical trials of TRE (without calorie counting) on body weight and metabolic risk factors. The efficacy of TRE in various populations groups, including those with obesity, type 2 diabetes (T2DM), and polycystic ovary syndrome (PCOS), is also examined.

Indexed as

Diabetes Mellitus, Type 2Polycystic Ovary SyndromeEatingEnergy IntakeFastingFemaleHumansObesityRisk Factorsglycemic controlintermittent fastingmetabolic riskobesitypolycystic ovary syndromeprediabetestime-restricted eatingtype 2 diabetesweight loss

Identifiers

PMID38176412
PMCPMC11221496

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.