ReviewDiabetology & metabolic syndrome2024
Interventions in preconception and pregnant women at risk of gestational diabetes; a systematic review and meta-analysis of randomised controlled trials.
Review in Diabetology & metabolic syndrome, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Preconception Interventions in Women at High Risk of Developing Gestational Diabetes: A Systematic Review.Maternal and child health journal · 2026Pooled it
- Evaluating acceptability and experiences of pregnant women at high risk of developing gestational diabetes who take part in antenatal intervention trials: a qualitative systematic review.BMC pregnancy and childbirth · 2025Pooled it
- 25-Hydroxyvitamin D, Vitamin D Binding Protein and Gestational Diabetes Mellitus: A Two-Sample Mendelian Randomization Study.Nutrients · 2024Pooled it
- Association between polycystic ovary syndrome and pregnancy outcomes in GDM: A secondary analysis of the DiGest trial.The Journal of clinical endocrinology and metabolism · 2026Trial
- Time restricted eating and exercise training before and during pregnancy for people with increased risk of gestational diabetes: single centre randomised controlled trial (BEFORE THE BEGINNING).BMJ (Clinical research ed.) · 2025Trial
- Externally validated risk prediction models for gestational diabetes mellitus: A systematic review and meta-analysis.Acta obstetricia et gynecologica Scandinavica · 2026Review
- [Management of hyperglycemia in pregnancy (Update 2026)].Wiener klinische Wochenschrift · 2026Review
- Predictive performance of artificial intelligence algorithms for gestational diabetes mellitus in pregnant women: a protocol for systematic review and meta-analysis.Systematic reviews · 2026Article
- Preconception Perceptions, Knowledge and Behaviours of Women With Gestational Diabetes Mellitus: A Qualitative Study.Health expectations : an international journal of public participation in health care and health policy · 2026Article
- Perspectives on preconception care in Ethiopia: Social, cultural, and structural determinants.PloS one · 2026Article
- Racial disparities in the prevalence and perinatal outcomes of gestational diabetes among women with normal body mass index.Journal of diabetes investigation · 2026Observational
- Prevalence and risk factors of gestational diabetes mellitus among pregnant women in northern Vietnam: a cross-sectional study.Global health action · 2025Article
- Gestational Diabetes Mellitus: Efficacy of Non-Pharmacological Interventions for Management and Prevention.Healthcare (Basel, Switzerland) · 2025Review
- A narrative review of metformin in pregnancy: Navigating benefit and uncertainty.Diabetes, obesity & metabolism · 2025Review
- Effect of myo-inositol on the prevention of gestational diabetes in high-risk pregnant women: An RCT.International journal of reproductive biomedicine · 2025Article
- The long-term general practice healthcare of women with a history of gestational diabetes: A Scoping Review Protocol.HRB open research · 2025Article
- Physical Activity during Pregnancy and Risk of Gestational Diabetes Mellitus: A Meta-Review.Life (Basel, Switzerland) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundWomen at risk of gestational diabetes mellitus (GDM) need preventative interventions.
objectiveTo evaluate targeted interventions before and during pregnancy for women identified as being at risk of developing GDM.
methodsSystematic review and meta-analysis conducted following PRISMA guidelines. MEDLINE, EMBASE and the Cochrane Library in addition to reference and citation lists were searched to identify eligible randomised controlled trials (RCTs) utilising risk stratification during the preconception period or in the first/early second trimester. Screening and data extraction were carried out by the authors independently. Quality assessment was conducted based on the Cochrane risk-of-bias tool. Random effects meta-analysis and narrative synthesis were performed.
resultsEighty-four RCTs were included: two during preconception and 82 in pregnancy, with a pooled sample of 22,568 women. Interventions were behavioural (n = 54), dietary supplementation (n = 19) and pharmacological (n = 11). Predictive factors for risk assessment varied; only one study utilised a validated prediction model. Gestational diabetes was reduced in diet and physical activity interventions (risk difference - 0.03, 95% CI 0.06, - 0.01; I
conclusionsThis review provides evidence that interventions targeted at women at risk of GDM may be an effective strategy for prevention. Further studies using validated prediction tools or multiple risk factors to target high-risk women for intervention before and during pregnancy are warranted.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.