Evidence map›Paper›PMID 38182731›Full record

ArticleScientific reports2024

Seroincidence of SARS-CoV-2 infection prior to and during the rollout of vaccines in a community-based prospective cohort of U.S. adults.

Denis Nash, Avantika Srivastava, Yanhan Shen, Kate Penrose, Sarah G Kulkarni, Rebecca Zimba, William You, Amanda Berry, Chloe Mirzayi, Andrew Maroko and 3 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Denis NashInstitute for Implementation Science in Population Health (ISPH), City University of New York (CUNY), New York, NY, USA. denis.nash@sph.cuny.edu.
Avantika SrivastavaInstitute for Implementation Science in Population Health (ISPH), City University of New York (CUNY), New York, NY, USA.
Yanhan ShenInstitute for Implementation Science in Population Health (ISPH), City University of New York (CUNY), New York, NY, USA.
Kate PenroseInstitute for Implementation Science in Population Health (ISPH), City University of New York (CUNY), New York, NY, USA.
Sarah G KulkarniInstitute for Implementation Science in Population Health (ISPH), City University of New York (CUNY), New York, NY, USA.
Rebecca ZimbaInstitute for Implementation Science in Population Health (ISPH), City University of New York (CUNY), New York, NY, USA.
William YouInstitute for Implementation Science in Population Health (ISPH), City University of New York (CUNY), New York, NY, USA.
Amanda BerryInstitute for Implementation Science in Population Health (ISPH), City University of New York (CUNY), New York, NY, USA.
Chloe MirzayiInstitute for Implementation Science in Population Health (ISPH), City University of New York (CUNY), New York, NY, USA.
Andrew MarokoInstitute for Implementation Science in Population Health (ISPH), City University of New York (CUNY), New York, NY, USA.
Angela M ParcesepeInstitute for Implementation Science in Population Health (ISPH), City University of New York (CUNY), New York, NY, USA.
Christian GrovInstitute for Implementation Science in Population Health (ISPH), City University of New York (CUNY), New York, NY, USA.
McKaylee M RobertsonInstitute for Implementation Science in Population Health (ISPH), City University of New York (CUNY), New York, NY, USA.

Funding

Following a U.S. National Cohort of Vulnerable Men to Improve HIV Prevention and CareUH3AI133675 · NIAID · GRADUATE SCHOOL OF PUBLIC HEALTH AND HEALTH POLICY · PI GROV, CHRISTIAN · 2019 to 2021
$6.9M
Brief digital intervention to increase COVID-19 vaccination among individuals with anxiety or depressionRF1MH132360 · NIMH · GRADUATE SCHOOL OF PUBLIC HEALTH AND HEALTH POLICY · PI NASH, DENIS, PARCESEPE, ANGELA · 2022 to 2022
$3.3M
NIAID NIH HHS UH3 AI133675NIMH NIH HHS RF1 MH132360
6 · The paper itself

Abstract

This study used repeat serologic testing to estimate infection rates and risk factors in two overlapping cohorts of SARS-CoV-2 N protein seronegative U.S. adults. One mostly unvaccinated sub-cohort was tracked from April 2020 to March 2021 (pre-vaccine/wild-type era, n = 3421), and the other, mostly vaccinated cohort, from March 2021 to June 2022 (vaccine/variant era, n = 2735). Vaccine uptake was 0.53% and 91.3% in the pre-vaccine and vaccine/variant cohorts, respectively. Corresponding seroconversion rates were 9.6 and 25.7 per 100 person-years. In both cohorts, sociodemographic and epidemiologic risk factors for infection were similar, though new risk factors emerged in the vaccine/variant era, such as having a child in the household. Despite higher incidence rates in the vaccine/variant cohort, vaccine boosters, masking, and social distancing were associated with substantially reduced infection risk, even through major variant surges.

Indexed as

COVID-19VaccinesAdultChildHumansImmunization, SecondaryProspective StudiesSARS-CoV-2Vaccines

Identifiers

PMID38182731
PMCPMC10770061

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.