Evidence mapPaperPMID 38185713Full record

ReviewNatural products and bioprospecting2024

Flavonoids as dual-target inhibitors against α-glucosidase and α-amylase: a systematic review of in vitro studies.

Thua-Phong Lam, Ngoc-Vi Nguyen Tran, Long-Hung Dinh Pham, Nghia Vo-Trong Lai, Bao-Tran Ngoc Dang, Ngoc-Lam Nguyen Truong, Song-Ky Nguyen-Vo, Thuy-Linh Hoang, Tan Thanh Mai, Thanh-Dao Tran

Open access · diamondAbstract readReview
In one paragraph

Review in Natural products and bioprospecting, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
31.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 88 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Enzyme-Assisted Ultrasonic Extraction of Flavonoids fromAntioxidants (Basel, Switzerland) · 2026
    Article
  8. Article
  9. Article
  10. Exploring the Multifaceted Phytochemical Profile ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
  11. α-Glucosidase Inhibitory Potential ofFood science & nutrition · 2026
    Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Aqueous Extracts and Flavonoids Obtained fromPharmaceuticals (Basel, Switzerland) · 2025
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 4 countries.

Thua-Phong Lam *Faculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, 700000, Ho Chi Minh City, Vietnam.ORCID http://orcid.org/0000-0002-8149-9952
Ngoc-Vi Nguyen Tran *Faculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, 700000, Ho Chi Minh City, Vietnam.ORCID http://orcid.org/0000-0002-1724-9457
Long-Hung Dinh PhamFaculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, 700000, Ho Chi Minh City, Vietnam.ORCID http://orcid.org/0000-0003-1434-0375
Nghia Vo-Trong LaiFaculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, 700000, Ho Chi Minh City, Vietnam.ORCID http://orcid.org/0000-0002-0392-436X
Bao-Tran Ngoc DangFaculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, 700000, Ho Chi Minh City, Vietnam.ORCID http://orcid.org/0000-0001-8638-7805
Ngoc-Lam Nguyen TruongFaculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, 700000, Ho Chi Minh City, Vietnam.
Song-Ky Nguyen-VoFaculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, 700000, Ho Chi Minh City, Vietnam.
Thuy-Linh HoangCalifornia Northstate University College of Pharmacy, California, 95757, USA.ORCID http://orcid.org/0000-0002-5168-935X
Tan Thanh MaiFaculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, 700000, Ho Chi Minh City, Vietnam. mthtan@ump.edu.vn.ORCID http://orcid.org/0000-0001-7313-9853
Thanh-Dao TranFaculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, 700000, Ho Chi Minh City, Vietnam. daott@ump.edu.vn.ORCID http://orcid.org/0000-0003-4504-0279
University of Medicine and Pharmacy at Ho Chi Minh City · VNUppsala University · SECalifornia Northstate University · US

Funding

University of Medicine and Pharmacy at Ho Chi Minh City 162/2019/HĐ-ĐHYD
6 · The paper itself

Abstract

Diabetes mellitus remains a major global health issue, and great attention is directed at natural therapeutics. This systematic review aimed to assess the potential of flavonoids as antidiabetic agents by investigating their inhibitory effects on α-glucosidase and α-amylase, two key enzymes involved in starch digestion. Six scientific databases (PubMed, Virtual Health Library, EMBASE, SCOPUS, Web of Science, and WHO Global Index Medicus) were searched until August 21, 2022, for in vitro studies reporting IC

Indexed as

AmylaseDual-targetFlavonoidsGlucosidasePRISMASARSystematic review

Identifiers

PMID38185713
PMCPMC10772047
OpenAlexW4390655823

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.