Evidence map›Paper›PMID 38187693›Full record

ArticlebioRxiv : the preprint server for biology2023

The role of satellite cell-derived TRIM28 in mechanical load- and injury-induced myogenesis.

Kuan-Hung Lin, Jamie E Hibbert, Jake L Lemens, Melissa M Torbey, Nathaniel D Steinert, Philip M Flejsierowicz, Kiley M Melka, Marcos Lares, Vijayasaradhi Setaluri, Troy A Hornberger

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Kuan-Hung LinDepartment of Comparative Biosciences, University of Wisconsin - Madison, WI, USA.
Jamie E HibbertDepartment of Comparative Biosciences, University of Wisconsin - Madison, WI, USA.
Jake L LemensDepartment of Comparative Biosciences, University of Wisconsin - Madison, WI, USA.
Melissa M TorbeyDepartment of Comparative Biosciences, University of Wisconsin - Madison, WI, USA.
Nathaniel D SteinertDepartment of Comparative Biosciences, University of Wisconsin - Madison, WI, USA.
Philip M FlejsierowiczDepartment of Comparative Biosciences, University of Wisconsin - Madison, WI, USA.
Kiley M MelkaDepartment of Comparative Biosciences, University of Wisconsin - Madison, WI, USA.
Marcos LaresDepartment of Dermatology, University of Wisconsin - Madison, WI, USA.
Vijayasaradhi SetaluriDepartment of Dermatology, University of Wisconsin - Madison, WI, USA.
Troy A HornbergerDepartment of Comparative Biosciences, University of Wisconsin - Madison, WI, USA.ORCID 0000-0002-2349-1899
University of Wisconsin System · USUniversity of Wisconsin–Madison · US

Funding

Skin Diseases Research Center at the University of WisconsinP30AR066524 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI LONGLEY, B JACK · 2014 to 2018
$2.6M
The Role of TRIM28 Phosphorylation in the Mechanical Regulation of Skeletal Muscle - Re-entry SupplementR01AR074932 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI HORNBERGER, TROY A · 2020 to 2024
$2.0M
NIAMS NIH HHS P30 AR066524NIAMS NIH HHS R01 AR074932
6 · The paper itself

Abstract

Satellite cells are skeletal muscle stem cells that contribute to postnatal muscle growth, and they endow skeletal muscle with the ability to regenerate after a severe injury. Here we discovered that this myogenic potential of satellite cells requires a protein called tripartite motif-containing 28 (TRIM28). Unexpectedly, multiple lines of both

Identifiers

PMID38187693
PMCPMC10769277
OpenAlexW4390057623

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.