Evidence map›Paper›PMID 38193073›Full record

ArticleFrontiers in immunology2023

Serum proteomics reveals a tolerant immune phenotype across multiple pathogen taxa in wild vampire bats.

Amanda Vicente-Santos, Lauren R Lock, Meagan Allira, Kristin E Dyer, Annalise Dunsmore, Weihong Tu, Dmitriy V Volokhov, Claudia Herrera, Guang-Sheng Lei, Ryan F Relich and 4 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  15. Pathogens and planetary change.Nature reviews. Biodiversity · 2025
    Article
  16. Review
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Amanda Vicente-SantosSchool of Biological Sciences, University of Oklahoma, Norman, OK, United States.
Lauren R LockSchool of Biological Sciences, University of Oklahoma, Norman, OK, United States.
Meagan AlliraSchool of Biological Sciences, University of Oklahoma, Norman, OK, United States.
Kristin E DyerSchool of Biological Sciences, University of Oklahoma, Norman, OK, United States.
Annalise DunsmoreDepartment of Tropical Medicine, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, United States.
Weihong TuDepartment of Tropical Medicine, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, United States.
Dmitriy V VolokhovCenter for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, United States.
Claudia HerreraDepartment of Tropical Medicine, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, United States.
Guang-Sheng LeiDepartment of Pathology and Laboratory Medicine, School of Medicine, Indiana University, Indianapolis, IN, United States.
Ryan F RelichDepartment of Pathology and Laboratory Medicine, School of Medicine, Indiana University, Indianapolis, IN, United States.
Michael G JanechHollings Marine Laboratory, Charleston, SC, United States.
Alison M BlandHollings Marine Laboratory, Charleston, SC, United States.
Nancy B SimmonsDepartment of Mammalogy, Division of Vertebrate Zoology, American Museum of Natural History, New York, NY, United States.
Daniel J BeckerSchool of Biological Sciences, University of Oklahoma, Norman, OK, United States.

Funding

Vascular-macrophage crosstalk in GBM immunosuppressionP20GM134973 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Sree Deepthi Muthukrishnan · 2020 to 2026
$17.6M
NIGMS NIH HHS P20 GM134973
6 · The paper itself

Abstract

Bats carry many zoonotic pathogens without showing pronounced pathology, with a few exceptions. The underlying immune tolerance mechanisms in bats remain poorly understood, although information-rich omics tools hold promise for identifying a wide range of immune markers and their relationship with infection. To evaluate the generality of immune responses to infection, we assessed the differences and similarities in serum proteomes of wild vampire bats (

Indexed as

Chagas DiseaseChiropteraAnimalsBiomarkersDown-RegulationHumansPhenotypeProteomicsBiomarkersbacteriabiomarkerDesmodus rotundusprotozoashotgun proteomicsvirus

Identifiers

PMID38193073
PMCPMC10773587

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.