Evidence map›Paper›PMID 38195943›Full record

ArticleEuropean journal of applied physiology2024

Downhill running increases markers of muscle damage and impairs the maximal voluntary force production as well as the late phase of the rate of voluntary force development.

Giuseppe Coratella, Giorgio Varesco, Vianney Rozand, Benjamin Cuinet, Veronica Sansoni, Giovanni Lombardi, Gianluca Vernillo, Laurent Mourot

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of applied physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07113405 (The Influence of Tea Extract on Maximal Voluntary Knee Contraction After 30 Minutes of Downhill Jogging), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07113405 narecruitingnot on this mapstarted 2025, after this paper: background citation

The Influence of Tea Extract on Maximal Voluntary Knee Contraction After 30 Minutes of Downhill Jogging: a Randomized, Double-blind, Placebo-controlled Study

TypeinterventionalSponsorUniversity of FribourgRan2025 to 2026Enrolled60ConditionsMuscle RecoveryArmsProtein and tea extract, Protein, Placebo
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Giuseppe Coratella *Department of Biomedical Sciences for Health, Università Degli Studi Di Milano, Milan, Italy.ORCID http://orcid.org/0000-0001-7523-9102
Giorgio Varesco *Université Jean Monnet Saint-Etienne, Inter-University Laboratory of Human Movement Biology, 42023, Saint-Etienne, France.ORCID http://orcid.org/0000-0001-9385-6972
Vianney RozandUniversité Jean Monnet Saint-Etienne, Inter-University Laboratory of Human Movement Biology, 42023, Saint-Etienne, France.ORCID http://orcid.org/0000-0002-7479-1189
Benjamin CuinetPrognostic Factors and Regulatory Factors of Cardiac and Vascular Pathologies (EA3920), Exercise Performance Health Innovation (EPHI) Platform, University of Franche-Comté, Besançon, France.
Veronica SansoniLaboratory of Experimental Biochemistry and Molecular Biology, IRCCS Instituto Ortopedico Galeazzi, 20157, Milan, Italy.ORCID http://orcid.org/0000-0003-0337-975X
Giovanni LombardiLaboratory of Experimental Biochemistry and Molecular Biology, IRCCS Instituto Ortopedico Galeazzi, 20157, Milan, Italy.ORCID http://orcid.org/0000-0002-8365-985X
Gianluca VernilloDepartment of Biomedical Sciences for Health, Università Degli Studi Di Milano, Milan, Italy. gianluca.vernillo@gmail.com.ORCID http://orcid.org/0000-0003-2580-4470
Laurent MourotPrognostic Factors and Regulatory Factors of Cardiac and Vascular Pathologies (EA3920), Exercise Performance Health Innovation (EPHI) Platform, University of Franche-Comté, Besançon, France.ORCID http://orcid.org/0000-0001-9486-3090

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo examined the time-course of the early and late phase of the rate of voluntary force development (RVFD) and muscle damage markers after downhill running.

methodsTen recreational runners performed a 30-min downhill run at 10 km h

resultsMVIC showed moderate decrements (p < 0.05) and recovered after 4 days (p > 0.05). Force at 50 ms and the early phase were not impaired (p > 0.05). Conversely, force at 200 ms and the late phase showed moderate decrements (p < 0.05) and recovered after 3 and 4 days, respectively (p > 0.05). CK concentration, quadriceps swelling, and soreness increased (p < 0.05) were overall fully resolved after 4 days (p > 0.05).

conclusionDownhill running affected the knee extensors RVFD late but not early phase. The RVFD late phase may be used as an additional marker of muscle damage in trail running.

Indexed as

Creatine KinaseMyalgiaRunningAdultBiomarkersHumansIsometric ContractionMaleMuscle, SkeletalMuscle StrengthQuadriceps MuscleBiomarkersCreatine KinaseCreatine kinaseDelayed onset muscle sorenessEccentricMaximum voluntary contractionMuscle swellingMusculoskeletalQuadricepsTrail running

Identifiers

PMID38195943
PMCPMC11129977

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.