Evidence map›Paper›PMID 38199865›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024

Multidimensional Analysis of a Social Behavior Identifies Regression and Phenotypic Heterogeneity in a Female Mouse Model for Rett Syndrome.

Michael Mykins, Benjamin Bridges, Angela Jo, Keerthi Krishnan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Pubertal development is unaffected in femalemicroPublication biology · 2026
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Michael MykinsDepartment of Biochemistry & Cellular and Molecular Biology, University of Tennessee, Knoxville, Tennessee.
Benjamin BridgesDepartment of Biochemistry & Cellular and Molecular Biology, University of Tennessee, Knoxville, Tennessee.
Angela JoDepartment of Biochemistry & Cellular and Molecular Biology, University of Tennessee, Knoxville, Tennessee.
Keerthi KrishnanDepartment of Biochemistry & Cellular and Molecular Biology, University of Tennessee, Knoxville, Tennessee krishnan@utk.edu.
University of Tennessee at Knoxville · US

Funding

Role of Piriform Cortex Perineuronal Nets in Mouse Social Communication.R15MH124042 · NIMH · UNIVERSITY OF TENNESSEE KNOXVILLE · PI KRISHNAN, KEERTHI · 2020 to 2020
$451k
NIMH NIH HHS R15 MH124042
6 · The paper itself

Abstract

Regression is a key feature of neurodevelopmental disorders such as autism spectrum disorder, Fragile X syndrome, and Rett syndrome (RTT). RTT is caused by mutations in the X-linked gene methyl-CpG-binding protein 2 (

Indexed as

Autism Spectrum DisorderRett SyndromeAnimalsDisease Models, AnimalFemaleHumansMethyl-CpG-Binding Protein 2MiceMutationPhenotypeSocial BehaviorMethyl-CpG-Binding Protein 2behavioral heterogeneityfemale micepose estimationpup retrievalregressionRett syndrome

Identifiers

PMID38199865
PMCPMC10957218
OpenAlexW4390691763

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.