Evidence map›Paper›PMID 38200767›Full record

ArticleAnimals : an open access journal from MDPI2023

Evaluation of the Effectiveness of Medical-Grade Honey and Hypericum Perforatum Ointment on Second-Intention Healing of Full-Thickness Skin Wounds in Cats.

Kyriakos Chatzimisios, Vassiliki Tsioli, Georgia D Brellou, Emmanouela P Apostolopoulou, Vasileia Angelou, Emmanouil D Pratsinakis, Niels A J Cremers, Lysimachos G Papazoglou

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Pioneering Advances in Veterinary Medicine: From Diagnosis to Treatment.Animals : an open access journal from MDPI · 2025
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Kyriakos ChatzimisiosUnit of Surgery and Obstetrics, Companion Animal Clinic, School of Veterinary Medicine, Faculty of HealthSciences, Aristotle University of Thessaloniki, 54627 Thessaloniki, Greece.
Vassiliki TsioliClinic of Surgery, School of Veterinary Medicine, University of Thessaly, 224 Trikalon Street, Box Office 199, 43100 Karditsa, Greece.
Georgia D BrellouLaboratory of Pathology, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0003-0588-7256
Emmanouela P ApostolopoulouLaboratory of Pathology, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-7642-7946
Vasileia AngelouUnit of Surgery and Obstetrics, Companion Animal Clinic, School of Veterinary Medicine, Faculty of HealthSciences, Aristotle University of Thessaloniki, 54627 Thessaloniki, Greece.ORCID 0000-0002-1473-2400
Emmanouil D PratsinakisLaboratory of Agronomy, School of Agriculture, Faculty of Agriculture, Forestry and Natural Environment, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-3725-3525
Niels A J CremersDepartment of Gynecology and Obstetrics, Maastricht University Medical Center, 6202 AZ Maastricht, The Netherlands.ORCID 0000-0003-4042-8987
Lysimachos G PapazoglouUnit of Surgery and Obstetrics, Companion Animal Clinic, School of Veterinary Medicine, Faculty of HealthSciences, Aristotle University of Thessaloniki, 54627 Thessaloniki, Greece.ORCID 0000-0001-5471-4584
Aristotle University of Thessaloniki · GRUniversity Medical Center · USUniversity of Thessaly · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to determine the effects of two topical treatments on second-intention wound healing in cats. Eight 2 × 2 cm full-thickness wounds were created, four on each side of the dorsal midline of eight laboratory cats, to receive either medical-grade honey ointment (MGH) and its control (HC), or Hypericum-based ointment (HP) and its control (HPC). MGH or HP ointment was applied to four wounds on the same side, while the remaining four were used as controls, chosen at random. Planimetry, laser Doppler flowmetry, daily physical examinations, and histologic examinations on days 0, 7, 14, and 25 were used to assess the healing of wounds. Tissue perfusion was better in the MGH-treated (2.14 ± 0.18 mm/s) and HP-treated wounds (2.02 ± 0.13 mm/s) than in the untreated controls HC (1.59 ± 0.11 mm/s) and HPC (1.60 ± 0.05 mm/s), respectively (

Indexed as

cathoneyHypericumwound healing

Identifiers

PMID38200767
PMCPMC10778018
OpenAlexW4390051573

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.