Evidence map›Paper›PMID 38200993›Full record

ArticleHealthcare (Basel, Switzerland)2023

Does the Response to a Stressful Condition in Older Adults with Life Rhythm Dysregulations Provide Evidence of the Existence of the "Dysregulation of Mood, Energy, and Social Rhythms Syndrome"?

Diego Primavera, Cesar Ivan Aviles Gonzalez, Ferdinando Romano, Goce Kalcev, Samantha Pinna, Luigi Minerba, Alessandra Scano, Germano Orrù, Giulia Cossu

Open access · goldAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Social Rhythms, Depressive Symptoms, and Quality of Life: An Unbreakable Bond in an Older Adult Sample.International journal of environmental research and public health · 2026
    Observational
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  8. Virtual reality, social intelligence, mirror neurons, and bipolar spectrum: a new perspective.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Diego PrimaveraDepartment of Medical Sciences and Public Health, University of Cagliari, 09042 Cagliari, Italy.
Cesar Ivan Aviles GonzalezDepartment of Medical Sciences and Public Health, University of Cagliari, 09042 Cagliari, Italy.ORCID 0000-0002-1566-1974
Ferdinando RomanoChair of Public Health, La Sapienza University, Rome, Italy 00185 Rome, Italy.
Goce KalcevDepartment of Medical Sciences and Public Health, University of Cagliari, 09042 Cagliari, Italy.ORCID 0000-0002-0351-6577
Samantha PinnaDepartment of Medical Sciences and Public Health, University of Cagliari, 09042 Cagliari, Italy.ORCID 0009-0005-5152-3834
Luigi MinerbaDepartment of Medical Sciences and Public Health, University of Cagliari, 09042 Cagliari, Italy.
Alessandra ScanoDepartment of Surgical Sciences, University of Cagliari, 09042 Cagliari, Italy.ORCID 0000-0002-4385-8002
Germano OrrùDepartment of Surgical Sciences, University of Cagliari, 09042 Cagliari, Italy.ORCID 0000-0003-1032-4431
Giulia CossuDepartment of Medical Sciences and Public Health, University of Cagliari, 09042 Cagliari, Italy.ORCID 0000-0002-1245-016X
University of Cagliari · ITSapienza University of Rome · IT

Funding

Fondazione di Sardegna SARDEGNA F.S.E. 2014-2020
6 · The paper itself

Abstract

objectiveThe COVID-19 lockdown periods have given rise to the "Dysregulation of Mood, Energy, and Social Rhythms Syndrome" (DYMERS). This syndrome is characterized by a poor regulation of biological, social, and behavioral rhythms, including sleep, nutrition, and social contacts. The purpose of this cohort study was to examine whether older adults with pre-existing DYMERS had a more negative perception of their health-related quality of life (H-QoL) during the COVID-19 pandemic lockdown, regardless of the presence of concurrent mood disorders.

methodThe entire study population (

resultsThe frequency of individuals with a critical health-related quality of life score (SF12 < 25) was higher in the cohort with pre-existing DYMERS during lockdown (33.33% vs. 6.17%). This difference remained significant even when only individuals without depressive symptomatology were considered (27.27% vs. 2.60%).

conclusionThe results of this study indicate that DYMERS can exert a substantial influence on health-related quality of life (H-QoL), even when mood disturbances are not present. Additional research is required to investigate the relationship between DYMERS and other psychiatric conditions as well as its nature as a standalone disorder.

Indexed as

behavioral rhythmsbiological rhythmsCOVID-19 pandemicquality of lifesocial rhythms

Identifiers

PMID38200993
PMCPMC10778618
OpenAlexW4390403413

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.