Evidence map›Paper›PMID 38201219›Full record

ReviewCells2023

Pathophysiological Effects of Autoantibodies in Autoimmune Encephalitides.

Matias Ryding, Anne With Mikkelsen, Mette Scheller Nissen, Anna Christine Nilsson, Morten Blaabjerg

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Autoimmune Encephalitis in Acute Care-Pathology, Diagnosis, and Management.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Matias RydingDepartment of Clinical Research, University of Southern Denmark, 5000 Odense, Denmark.ORCID 0000-0003-1151-7497
Anne With MikkelsenDepartment of Clinical Immunology, Odense University Hospital, 5000 Odense, Denmark.
Mette Scheller NissenDepartment of Neurology, Odense University Hospital, 5000 Odense, Denmark.ORCID 0000-0002-3512-3479
Anna Christine NilssonDepartment of Clinical Research, University of Southern Denmark, 5000 Odense, Denmark.
Morten BlaabjergDepartment of Clinical Research, University of Southern Denmark, 5000 Odense, Denmark.ORCID 0000-0001-6007-1861
University of Southern Denmark · DKOdense University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The heterogeneity of autoantibody targets in autoimmune encephalitides presents a challenge for understanding cellular and humoral pathophysiology, and the development of new treatment strategies. Thus, current treatment aims at autoantibody removal and immunosuppression, and is primarily based on data generated from other autoimmune neurological diseases and expert consensus. There are many subtypes of autoimmune encephalitides, which now entails both diseases with autoantibodies targeting extracellular antigens and classical paraneoplastic syndromes with autoantibodies targeting intracellular antigens. Here, we review the current knowledge of molecular and cellular effects of autoantibodies associated with autoimmune encephalitis, and evaluate the evidence behind the proposed pathophysiological mechanisms of autoantibodies in autoimmune encephalitis.

Indexed as

Autoimmune Diseases of the Nervous SystemEncephalitisHashimoto DiseaseAutoantibodiesConsensusHumansAutoantibodiesautoimmune encephalitidesmolecular mechanismsneuroinflammation

Identifiers

PMID38201219
PMCPMC10778077
OpenAlexW4390007749

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.