Evidence map›Paper›PMID 38201653›Full record

ArticleCancers2024

Changes in the Incidence and Human Papillomavirus-Positive Portion of Oropharyngeal Squamous Cell Carcinoma in Hong Kong.

Zigui Chen, Amy B W Chan, Lok-Sang Kam, Man-Hin Chan, Jason Y K Chan, Wai-Tung Lee, Chit Chow, Siaw S Boon, Chichao Xia, Brian Lam and 6 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Zigui ChenDepartment of Microbiology, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-8577-1298
Amy B W ChanDepartment of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-9272-6380
Lok-Sang KamDepartment of Anatomical Pathology, Tuen Mun Hospital, Hong Kong SAR, China.
Man-Hin ChanDepartment of ENT, Yan Chai Hospital, Hong Kong SAR, China.
Jason Y K ChanDepartment of Otorhinolaryngology, Head and Neck Surgery, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-9480-4637
Wai-Tung LeeDepartment of Pathology, Queen Elizabeth Hospital, Hong Kong SAR, China.
Chit ChowDepartment of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong SAR, China.
Siaw S BoonDepartment of Microbiology, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0001-9772-2971
Chichao XiaDepartment of Microbiology, The Chinese University of Hong Kong, Hong Kong SAR, China.
Brian LamDepartment of ENT, Yan Chai Hospital, Hong Kong SAR, China.ORCID 0000-0002-7023-4203
Suki LamDepartment of ENT, Yan Chai Hospital, Hong Kong SAR, China.
Rita W Y NgDepartment of Microbiology, The Chinese University of Hong Kong, Hong Kong SAR, China.
Wendy C S HoDepartment of Microbiology, The Chinese University of Hong Kong, Hong Kong SAR, China.
Eddy W H LamDepartment of ENT, Yan Chai Hospital, Hong Kong SAR, China.
Christopher K C LaiDepartment of Microbiology, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0001-8591-5944
Paul K S ChanDepartment of Microbiology, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-6360-4608
Chinese University of Hong Kong · HKQueen Elizabeth Hospital · CNTuen Mun Hospital · CN

Funding

MSD (United States) MISP59351
6 · The paper itself

Abstract

The incidence of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) is rising in the West, but little is known in Asia. This study elucidated changes in the incidence and HPV-positive portion of OPSCC in Hong Kong. Data from population-based cancer registry were used to analyze the incidence of OPSCC in association with other head and neck cancers. Archived tumor tissues were tested for HPV. From 1986 to 2020, there was a marked decrease in the incidence of nasopharyngeal and laryngeal cancers, but a persistent increase in OPSCC from 36 cases in 1986 to 116 cases in 2020. The average positive rate for high-risk HPV was 36.1% (112/310) among OPSCC diagnosed in 2010-2020. The HPV-positive rate in recent years was significantly higher than earlier cases (tonsil SCC: 64.7% (55/85) in 2016-2020 vs. 40.4% (19/47) in 2010-2015,

Indexed as

Chinesehead and neck cancersHong KongHPVOPSCCoropharyngeal cancertonsil cancer

Identifiers

PMID38201653
PMCPMC10778352
OpenAlexW4390538776

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.