Evidence map›Paper›PMID 38201926›Full record

Trial reportNutrients2023

Evaluating the Impact of Omega-3 Fatty Acid (Soloways

Evgeny Pokushalov, Andrey Ponomarenko, Sevda Bayramova, Claire Garcia, Inessa Pak, Evgenya Shrainer, Elena Voronina, Ekaterina Sokolova, Michael Johnson, Richard Miller

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06154408 (Evaluating the Impact of Omega-3 Fatty Acid Supplementation), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06154408 nacompletednot on this map

Evaluating the Impact of Omega-3 Fatty Acid Supplementation (Soloways™) on Lipid Profiles in Adults With PPARG Polymorphisms: A Randomized, Double-blind, Placebo-controlled Trial

TypeinterventionalSponsorS.LAB (SOLOWAYS)Ran2022 to 2022Enrolled102ConditionsLDL Hyperlipoproteinemia, Low-Density-Lipoprotein-Type [LDL] Hyperlipoproteinemia, Triglyceride Storage Type I or II DiseaseArmsomega-3 fatty acids, Placebo
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
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  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Evgeny PokushalovCenter for New Medical Technologies, 630090 Novosibirsk, Russia.ORCID 0000-0002-9494-4234
Andrey PonomarenkoCenter for New Medical Technologies, 630090 Novosibirsk, Russia.ORCID 0000-0002-5468-9961
Sevda BayramovaCenter for New Medical Technologies, 630090 Novosibirsk, Russia.
Claire GarciaScientific Research Laboratory, Triangel Scientific, San Francisco, CA 94101, USA.
Inessa PakCenter for New Medical Technologies, 630090 Novosibirsk, Russia.
Evgenya ShrainerCenter for New Medical Technologies, 630090 Novosibirsk, Russia.ORCID 0000-0002-9675-3044
Elena VoroninaInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.ORCID 0000-0002-3405-6980
Ekaterina SokolovaInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.ORCID 0000-0002-4852-5661
Michael JohnsonScientific Research Laboratory, Triangel Scientific, San Francisco, CA 94101, USA.
Richard MillerScientific Research Laboratory, Triangel Scientific, San Francisco, CA 94101, USA.

Funding

S.Lab (SOLOWAYS), LTD #29101
6 · The paper itself

Abstract

Emerging evidence suggests that PPARG gene polymorphisms may influence lipid metabolism and cardiovascular risk, with omega-3 fatty acids proposed to modulate these effects. This study aims to assess the effects of fish oil supplementation on cardiovascular markers among adults with PPARG gene polymorphisms in a randomized, double-blind, placebo-controlled trial. A cohort of 102 patients with LDL-C 70-190 mg/dL was randomized to receive either 2000 mg of omega-3 fatty acids or a placebo daily for 90 days. In the omega-3 group with PPARG polymorphisms, LDL-C was reduced by 15.4% (95% CI: -19.8% to -11.0%), compared with a 2.6% decrease in the placebo group (95% CI: -4.1% to -1.1%;

Indexed as

Fatty Acids, Omega-3AdultCholesterol, LDLDietary SupplementsHumansPolymorphism, GeneticPPAR gammaTriglyceridesCholesterol, LDLFatty Acids, Omega-3PPAR gammaTriglyceridescardiovascular healthLDL-Comega-3 fatty acidspersonalized medicinePPARG polymorphismstriglycerides

Identifiers

PMID38201926
PMCPMC10780403

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.