Evidence map›Paper›PMID 38211562›Full record

ArticleCell host & microbe2024

Better than being aPARt: S. aureus itches to get close to sensory neurons.

Zhe Chen, Sha Huang, Yanlin Su

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell host & microbe, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Zhe ChenSchool of Physical Education and Sports Science, South China Normal University, Guangzhou 510006, China.
Sha HuangResearch Center for Tissue Repair and Regeneration affiliated with the Medical Innovation Research Department, Chinese PLA General Hospital, Beijing 100853, China.
Yanlin SuResearch Center for Tissue Repair and Regeneration affiliated with the Medical Innovation Research Department, Chinese PLA General Hospital, Beijing 100853, China. Electronic address: suyl1166@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a recent issue of Cell, Deng et al. show that S. aureus serine protease V8 triggers itch, independent of inflammation, by activating sensory neurons through PAR1. This study presents mechanistic insights into pruritogenic bacteria and their interactions with sensory neurons while providing a possible approach for treating itch-related diseases.

Indexed as

Methicillin-Resistant Staphylococcus aureusStaphylococcus aureusHumansInflammationPruritusSensory Receptor Cells

Identifiers

PMID38211562

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.