ArticleNature communications2024
A CYBDOM protein impacts iron homeostasis and primary root growth under phosphate deficiency in Arabidopsis.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 30 citations in OpenAlex.
- Organic acids counteract the determinate root development induced by phosphate deprivation inPlant signaling & behavior · 2026Article
- Classical Phytohormones and Peptide Plant Hormones in Abiotic Stress Tolerance: Crosstalk, Physiological Integration, and Crop Improvement.Plants (Basel, Switzerland) · 2026Review
- Electron currents mediated by tonoplast cytochromes b561.European biophysics journal : EBJ · 2026Review
- Arbuscular mycorrhizal fungi regulate mineral element distribution in grapevines under pH stress.Frontiers in plant science · 2026Article
- Arabidopsis IONIC CURRENT FAMILY A proteins facilitate environmental calcium acquisition essential for stress tolerance.Nature plants · 2026Article
- ALUMINUM-ACTIVATED MALATE TRANSPORTER 1 (ALMT1) partially acidifies the rhizosphere in Pi deficiency-induced inhibition of primary root growth.Plant signaling & behavior · 2025Article
- Genetically Reprogramming Crops and Rhizobacteria for Nutritional Iron Biofortification.ACS synthetic biology · 2025Review
- HNature communications · 2025Article
- Plasma membrane CYBDOM proteins catalyse apoplastic AsA regeneration and interact with RbohD to activate autophagy and drought tolerance in plants.Nature plants · 2025Article
- Transcriptome- and Metabolome-Based Regulation of Growth, Development, and Bioactive Compounds inInternational journal of molecular sciences · 2025Article
- Overexpression ofGenes · 2025Article
- Barriers and carriers for transition metal homeostasis in plants.Plant communications · 2025Review
- Untangling iron threads: A deep dive into plant intracellular pools.Quantitative plant biology · 2025Review
- Physiological and transcriptional analyses of Arabidopsis primary root growth in response to phosphate starvation under light and dark conditions.Frontiers in plant science · 2025Article
- Phosphate promotes Arabidopsis root skewing and circumnutation through reorganisation of the microtubule cytoskeleton.The New phytologist · 2024Article
- The Phosphorus-Iron Nexus: Decoding the Nutrients Interaction in Soil and Plant.International journal of molecular sciences · 2024Review
- Recent advances in research on phosphate starvation signaling in plants.Journal of plant research · 2024Review
- Ferric reduction by a CYBDOM protein counteracts increased iron availability in root meristems induced by phosphorus deficiency.Nature communications · 2024Article
- Single Phototrophic Bacterium-Mediated Iron Cycling in Aquatic Environments.Research (Washington, D.C.) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
Arabidopsis primary root growth response to phosphate (Pi) deficiency is mainly controlled by changes in apoplastic iron (Fe). Upon Pi deficiency, apoplastic Fe deposition in the root apical meristem activates pathways leading to the arrest of meristem maintenance and inhibition of cell elongation. Here, we report that a member of the uncharacterized cytochrome b561 and DOMON domain (CYBDOM) protein family, named CRR, promotes iron reduction in an ascorbate-dependent manner and controls apoplastic iron deposition. Under low Pi, the crr mutant shows an enhanced reduction of primary root growth associated with increased apoplastic Fe in the root meristem and a reduction in meristematic cell division. Conversely, CRR overexpression abolishes apoplastic Fe deposition rendering primary root growth insensitive to low Pi. The crr single mutant and crr hyp1 double mutant, harboring a null allele in another member of the CYDOM family, shows increased tolerance to high-Fe stress upon germination and seedling growth. Conversely, CRR overexpression is associated with increased uptake and translocation of Fe to the shoot and results in plants highly sensitive to Fe excess. Our results identify a ferric reductase implicated in Fe homeostasis and developmental responses to abiotic stress, and reveal a biological role for CYBDOM proteins in plants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.