Trial reportScientific reports2024
A randomized controlled trial comparing different sites of high-velocity low amplitude thrust on sensorimotor integration parameters.
Trial report in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 12 citations in OpenAlex.
- Neck proprioception and mobility improved after upper neck and spine treatment: a randomized controlled trial.Experimental brain research · 2026Trial
- Immediate effects of upper cervical spinal manipulation on cervical sensorimotor control in individuals with chronic primary cervical pain: an exploratory randomized controlled trial.Chiropractic & manual therapies · 2026Trial
- The cervico-ocular reflex changes following treatment in individuals with subclinical neck pain: a randomized control trial.Experimental brain research · 2024Trial
- Upper cervical chiropractic management of a patient with headaches, neck pain and a history of traumatic internal carotid artery compromise: a case report.The Journal of manual & manipulative therapy · 2026Article
- Chiropractic Care Is Associated with Frequency-Specific Reorganisation of Triple-Network Brain Dynamics: A Source-Localised EEG Study.Brain sciences · 2026Article
- Unique RNA Gene Expression Profile Is Seen in Chronic Non-Specific Low Back Pain.International journal of molecular sciences · 2025Article
- A comparative analysis of palpatory acuity in chiropractic students between 2015 and 2024.BMC medical education · 2025Article
- Tailored Rehabilitation Program and Dynamic Ultrasonography After Surgical Repair of Bilateral Simultaneous Quadriceps Tendon Rupture in a Patient Affected by Gout: A Case Report.Healthcare (Basel, Switzerland) · 2025Article
- The Impact of a Single Hip Manipulation on Quadriceps Activity and Performance: A Randomized Study.Biomedicines · 2025Article
- Neuromuscular Response to High-Velocity, Low-Amplitude Spinal Manipulation-An Overview.Medicina (Kaunas, Lithuania) · 2025Review
- Neuroplastic Responses to Chiropractic Care: Broad Impacts on Pain, Mood, Sleep, and Quality of Life.Brain sciences · 2024Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 6 countries.
Funding
Abstract
Increasing evidence suggests that a high-velocity, low-amplitude (HVLA) thrust directed at a dysfunctional vertebral segment in people with subclinical spinal pain alters various neurophysiological measures, including somatosensory evoked potentials (SEPs). We hypothesized that an HVLA thrust applied to a clinician chosen vertebral segment based on clinical indicators of vertebral dysfunction, in short, segment considered as "relevant" would significantly reduce the N30 amplitude compared to an HVLA thrust applied to a predetermined vertebral segment not based on clinical indicators of vertebral dysfunction or segment considered as "non-relevant". In this double-blinded, active-controlled, parallel-design study, 96 adults with recurrent mild neck pain, ache, or stiffness were randomly allocated to receiving a single thrust directed at either a segment considered as "relevant" or a segment considered as "non-relevant" in their upper cervical spine. SEPs of median nerve stimulation were recorded before and immediately after a single HVLA application delivered using an adjusting instrument (Activator). A linear mixed model was used to assess changes in the N30 amplitude. A significant interaction between the site of thrust delivery and session was found (F
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.