Evidence map›Paper›PMID 38217010›Full record

SynthesisRespiratory research2024

Hemoadsorption in acute respiratory distress syndrome patients requiring venovenous extracorporeal membrane oxygenation: a systematic review.

Wenli Li, Yuansen Chen, Duo Li, Xiangyan Meng, Ziquan Liu, Yanqing Liu, Haojun Fan

Abstract readSystematic Review
In one paragraph

Synthesis in Respiratory research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenli Li *Institute of Disaster and Emergency Medicine, Tianjin University, Tianjin, China.
Yuansen Chen *Institute of Disaster and Emergency Medicine, Tianjin University, Tianjin, China.
Duo LiInstitute of Disaster and Emergency Medicine, Tianjin University, Tianjin, China.
Xiangyan MengInstitute of Disaster and Emergency Medicine, Tianjin University, Tianjin, China.
Ziquan LiuInstitute of Disaster and Emergency Medicine, Tianjin University, Tianjin, China.
Yanqing LiuInstitute of Disaster and Emergency Medicine, Tianjin University, Tianjin, China. wglyqwglyq@163.com.
Haojun FanInstitute of Disaster and Emergency Medicine, Tianjin University, Tianjin, China. haojunfan86@163.com.

Funding

National Key Research and Development Program of China 2021YFC3002201
6 · The paper itself

Abstract

backgroundVenovenous extracorporeal membrane oxygenation (VV ECMO) has been widely used for severe acute respiratory distress syndrome (ARDS) in recent years. However, the role of hemoadsorption in ARDS patients requiring VV ECMO is unclear.

methodsTherefore, we conducted a systematic review to describe the effect of hemoadsorption on outcomes of ARDS patients requiring VV ECMO and elucidate the risk factors for adverse outcomes. We conducted and reported a systematic literature review based on the principles derived from the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. The systematic review searched Embase, CINHAL, and Pubmed databases for studies on ARDS patients receiving hemoadsorption and VV ECMO. The demographic data, clinical data and biological data of the patients were collected.

resultsWe ultimately included a total of 8 articles including 189 patients. We characterized the population both clinically and biologically. Our review showed most studies described reductions in inflammatory markers and fluid resuscitation drug dosage in ARDS patients with Coronavirus disease 2019 (COVID-19) or sepsis after hemoadsorption.

conclusionBecause most of the studies have the characteristics of high heterogeneity, we could only draw very cautious conclusions that hemoadsorption therapy may enhance hemodynamic stability in ARDS patients with COVID-19 or sepsis receiving VV ECMO support. However, our results do not allow us to draw conclusions that hemoadsorption could reduce inflammation and mortality. Prospective randomized controlled studies with a larger sample size are needed in the future to verify the role of hemoadsorption in ARDS patients requiring VV ECMO.

Indexed as

COVID-19Extracorporeal Membrane OxygenationRespiratory Distress SyndromeSepsisHumansProspective StudiesRetrospective StudiesAcute respiratory distress syndromeHemoadsorptionHemodynamic stabilityInflammationMortalityVenovenous extracorporeal membrane oxygenation

Identifiers

PMID38217010
PMCPMC10785465

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.