Evidence mapPaperPMID 38217610Full record

ReviewJournal of Parkinson's disease2024

Addressing Comorbidities in People with Parkinson's Disease: Considerations From An Expert Panel.

Camille Carroll, Carl E Clarke, Donald Grosset, Arshad Rather, Biju Mohamed, Miriam Parry, Prashanth Reddy, Robin Fackrell, Kallol Ray Chaudhuri

Abstract readReview
In one paragraph

Review in Journal of Parkinson's disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Incidence of hip fractures in persons with and without Parkinson's disease in Finland: a 15-year longitudinal study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Camille CarrollTranslational and Clinical Research Institute, Newcastle University, Newcastle, UK.
Carl E ClarkeUniversity of Birmingham and City Hospital, Birmingham, UK.
Donald GrossetUniversity of Glasgow, Glasgow, UK.
Arshad RatherUniversity College London Hospitals, London, UK.
Biju MohamedCardiff and Vale University Health Board, Cardiff, UK.
Miriam ParryParkinson Foundation Centre of Excellence, King's College Hospital NHS Foundation Trust, London, UK.
Prashanth ReddyKing's College London, London, UK.
Robin FackrellRoyal United Hospital Bath, Bath, UK.
Kallol Ray ChaudhuriParkinson Foundation Centre of Excellence, King's College Hospital NHS Foundation Trust, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the UK, guidance exists to aid clinicians and patients deciding when treatment for Parkinson's disease (PD) should be initiated and which therapies to consider. National Institute for Health and Care Excellence (NICE) guidance recommends that before starting PD treatment clinicians should discuss the following: the patient's individual clinical circumstances; lifestyle; preferences; needs and goals; as well as the potential benefits and harms of the different drug classes. Individualization of medicines and management in PD significantly improves patients' outcomes and quality of life. This article aims to provide simple and practical guidance to help clinicians address common, but often overlooked, co-morbidities. A multi-disciplinary group of PD experts discussed areas where clinical care can be improved by addressing commonly found co-morbidities in people with Parkinson's (PwP) based on clinical experience and existing literature, in a roundtable meeting organized and funded by Bial Pharma UK Ltd. The experts identified four core areas (bone health, cardiovascular risk, anticholinergic burden, and sleep quality) that, if further standardized may improve treatment outcomes for PwP patients. Focusing on anticholinergic burden, cardiac risk, sleep, and bone health could offer a significant contribution to personalizing regimes for PwP and improving overall patient outcomes. Within this opinion-based paper, the experts offer a list of guiding factors to help practitioners in the management of PwP.

Indexed as

Parkinson DiseaseCholinergic AntagonistsHumansLife StyleQuality of LifeSleepCholinergic Antagonistsanticholinergicsbone densitycardiovascular riskclinical guidelinesindividualized treatmentParkinson’s diseasesleep quality

Identifiers

PMID38217610
PMCPMC10836549

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.