Evidence mapPaperPMID 38217713Full record

ArticleMikrochimica acta2024

An impedance labeling free electrochemical aptamer sensor based on tetrahedral DNA nanostructures for doxorubicin determination.

Dan Ou, Huixian Yan, Zuanguang Chen

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Dan OuDepartment of Pharmacy, The Second Affiliated Hospital of Guangxi Medical University, Nanning, 530007, China.
Huixian YanDepartment of Interventional Radiology, Guangxi Academy of Medical Science, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, 530016, China.
Zuanguang ChenSchool of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China. chenzg@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0002-0405-2911
Sun Yat-sen University · CNThe People's Hospital of Guangxi Zhuang Autonomous Region · CN

Funding

National Natural Science Foundation of China 21675177Youth Science Foundation of Guangxi Medical University GXMUYSF202338
6 · The paper itself

Abstract

Based on the electrochemical impedance method, a marker-free biosensor with aptamer as a biometric element was developed for the determination of doxorubicin (DOX). By combining aptamer with rigid tetrahedral DNA nanostructures (TDNs) and fixing them on the surface of gold electrode (GE) as biometric elements, the density and directivity of surface nanoprobes improved, and DOX was captured with high sensitivity and specificity. DOX was captured by immobilized aptamers on the GE, which inhibited electron transfer between the GE and [Fe(CN)6]

Indexed as

Aptamers, NucleotideNanostructuresDNADoxorubicinElectric ImpedanceGoldAptamers, NucleotideDNADoxorubicinGoldAptamerDoxorubicinElectrochemical impedance spectroscopySensorTetrahedral DNA nanostructure

Identifiers

PMID38217713
OpenAlexW4390841914

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.