Evidence map›Paper›PMID 38223830›Full record

ReviewJournal of ginseng research2024

Atypical formations of gintonin lysophosphatidic acids as new materials and their beneficial effects on degenerative diseases.

Ji-Hun Kim, Ra Mi Lee, Hyo-Bin Oh, Tae-Young Kim, Hyewhon Rhim, Yoon Kyung Choi, Jong-Hoon Kim, Seikwan Oh, Do-Geun Kim, Ik-Hyun Cho and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of ginseng research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Ji-Hun KimGinsentology Research Laboratory and Department of Physiology, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea.
Ra Mi LeeGinsentology Research Laboratory and Department of Physiology, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea.
Hyo-Bin OhDepartment of Efficacy Study, Institute of Jinan Red Ginseng, Jeollabuk-do, Republic of Korea.
Tae-Young KimDepartment of Efficacy Study, Institute of Jinan Red Ginseng, Jeollabuk-do, Republic of Korea.
Hyewhon RhimCenter for Neuroscience, Korea Institute of Science and Technology, Bio/Molecular Informatics Center, Republic of Korea.
Yoon Kyung ChoiDepartment of Bioscience and Biotechnology, Konkuk University, Seoul, Republic of Korea.
Jong-Hoon KimCollege of Veterinary Medicine, Biosafety Research Institute, Chonbuk National University, Jeollabuk-do, Republic of Korea.
Seikwan OhDepartment of Molecular Medicine, School of Medicine, Ewha Womans University, Seoul, Republic of Korea.
Do-Geun KimDementia Research Group, Korea Brain Research Institute, Daegu, Republic of Korea.
Ik-Hyun ChoDepartment of Convergence Medical Science, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
Seung-Yeol NahGinsentology Research Laboratory and Department of Physiology, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea.
Konkuk University · KRKorean Society of Ginseng · KREwha Womans University · KRKorea Brain Research Institute · KRKorea Institute of Science and Technology · KRKyung Hee University Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fresh ginseng is prone to spoilage due to its high moisture content. For long-term storage, most fresh ginsengs are dried to white ginseng (WG) or steamed for hours at high temperature/pressure and dried to form Korean Red ginseng (KRG). They are further processed for ginseng products when subjected to hot water extraction/concentration under pressure. These WG or KRG preparation processes affect ginsenoside compositions and also other ginseng components, probably during treatments like steaming and drying, to form diverse bioactive phospholipids. It is known that ginseng contains high amounts of gintonin lysophosphatidic acids (LPAs). LPAs are simple lipid-derived growth factors in animals and humans and act as exogenous ligands of six GTP-binding-protein coupled LPA receptor subtypes. LPAs play diverse roles ranging from brain development to hair growth in animals and humans. LPA-mediated signaling pathways involve various GTP-binding proteins to regulate downstream pathways like [Ca

Indexed as

Degenerative diseasesGinsengginseng-derived neurotrophinGintonin lysophosphatidic acidsNew material

Identifiers

PMID38223830
PMCPMC10785247
OpenAlexW4321439131

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.