Evidence map›Paper›PMID 38225280›Full record

ArticleScientific reports2024

Synthesis, structural characterizations, in vitro biological evaluation and computational investigations of pyrazole derivatives as potential antidiabetic and antioxidant agents.

Salma Mortada, Khalid Karrouchi, El Hadki Hamza, Afaf Oulmidi, Mashooq Ahamd Bhat, Hassane Mamad, Youssra Aalilou, Smaail Radi, M'hammed Ansar, Azlarab Masrar and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
16.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 67 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Salma MortadaLaboratory of Pharmacology and Toxicology, Biopharmaceutical and Toxicological Analysis Research Team, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco.
Khalid KarrouchiLaboratory of Analytical Chemistry and Bromatology, Team of Formulation and Quality Control of Health Products, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat, Morocco. khalid.karrouchi@um5s.net.ma.
El Hadki HamzaCERNE2D: Laboratory of Spectroscopy, Molecular Modelling, Materials, Nanomaterials, Water and Enviroment (LS3MN2E), Faculty of Sciences, Mohammed V University, Rabat, Morocco.
Afaf OulmidiInstitute of Condensed Matter and Nanosciences, Molecular Chemistry, Materials and Catalysis (IMCN/MOST), Université Catholique de Louvain, 1348, Louvain-la-Neuve, Belgium.
Mashooq Ahamd BhatDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, 11451, Riyadh, Saudi Arabia.
Hassane MamadCentral Laboratory of Hematology, Ibn Sina Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco.
Youssra AalilouLaboratory of Pharmacology and Toxicology, Biopharmaceutical and Toxicological Analysis Research Team, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco.
Smaail RadiLaboratoire de Chimie Appliquée et Environnement (LCAE), Faculté des Sciences, Université Mohammed I, 60000, Oujda, Morocco.
M'hammed AnsarLaboratory of Medicinal Chemistry, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco.
Azlarab Masrar *Central Laboratory of Hematology, Ibn Sina Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco.
My El Abbes Faouzi *Laboratory of Pharmacology and Toxicology, Biopharmaceutical and Toxicological Analysis Research Team, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco.
Mohammed V University · MAKing Saud University · SAUCLouvain · BEUniversité Hassan II Mohammedia · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, a two pyrazole derivatives; 2-(5-methyl-1H-pyrazole-3-carbonyl)-N-phenylhydrazine-1-carboxamide (Pyz-1) and 4-amino-5-(5-methyl-1H-pyrazol-3-yl)-4H-1,2,4-triazole-3-thiol (Pyz-2) were synthesized and characterized by

Indexed as

Diabetes MellitusHypoglycemic Agentsalpha-Amylasesalpha-GlucosidasesAntioxidantsGlycoside Hydrolase InhibitorsHumansMolecular Docking SimulationMolecular StructurePyrazolesSpectroscopy, Fourier Transform InfraredStructure-Activity RelationshipXanthine Oxidasealpha-Amylasesalpha-GlucosidasesAntioxidantsGlycoside Hydrolase InhibitorsHypoglycemic AgentsPyrazolesXanthine Oxidase

Identifiers

PMID38225280
PMCPMC10789823
OpenAlexW4390898283

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.