Evidence map›Paper›PMID 38230545›Full record

ArticleJournal of biomedical materials research. Part A2024

Impact of formulation on solid oxygen-entrapping materials to overcome tumor hypoxia.

Megan K McGovern, Emily Witt, Ashley C Rhodes, Jinhee Kim, Vivian R Feig, Jianling Bi, Arielle B Cafi, Sam Hatfield, Ikenna Nwosu, James D Byrne

Open access · hybridAbstract read
In one paragraph

Article in Journal of biomedical materials research. Part A, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Gas entrapping materials for damage control.Advanced drug delivery reviews · 2026
    Review
  2. Healing in a bubble.Science (New York, N.Y.) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Megan K McGovernDepartment of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA.
Emily WittDepartment of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA.
Ashley C RhodesDepartment of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA.
Jinhee KimDepartment of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada.
Vivian R FeigDivision of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Jianling BiDepartment of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA.
Arielle B CafiDepartment of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA.
Sam HatfieldDepartment of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA.
Ikenna NwosuDepartment of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA.
James D ByrneDepartment of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA.ORCID 0000-0002-6436-2866
University of Iowa · USBrigham and Women's Hospital · US

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Jon C.D. Houtman · 2000 to 2026
$70.0M
Medical Scientist Training ProgramT32GM139776 · NIGMS · UNIVERSITY OF IOWA · PI Gordon F Buchanan · 2021 to 2026
$6.4M
R25 YES: Cancer Research Opportunities at IowaR25CA273964 · NCI · UNIVERSITY OF IOWA · PI Jon C.D. Houtman, Jessica C Sieren · 2023 to 2026
$1.4M
Exploiting Carbon Monoxide Biofoams to Radio-Sensitize Rectal Cancer Cells While Protecting Normal BowelK08CA276908 · NCI · UNIVERSITY OF IOWA · PI James Donald Byrne · 2023 to 2026
$1.0M
NCI NIH HHS K08 CA276908NCI NIH HHS P30 CA086862NCI NIH HHS R25 CA273964NIGMS NIH HHS T32 GM139776NIH HHS 1K08CA276908
6 · The paper itself

Abstract

Tumor hypoxia, resulting from rapid tumor growth and aberrant vascular proliferation, exacerbates tumor aggressiveness and resistance to treatments like radiation and chemotherapy. To increase tumor oxygenation, we developed solid oxygen gas-entrapping materials (O

Indexed as

NeoplasmsOxygenHumansTumor HypoxiaOxygeninterventional oncologyintratumoral oxygenpartial pressuretherapy resistance

Identifiers

PMID38230545
PMCPMC10984782
OpenAlexW4390948978

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.