Evidence map›Paper›PMID 38230992›Full record

ArticleMagnetic resonance in medicine2024

Evidence of

Biranavan Uthayakumar, Hany Soliman, Albert P Chen, Nadia Bragagnolo, Nicole I C Cappelletto, Ruby Endre, William J Perks, Nathan Ma, Chris Heyn, Kayvan R Keshari and 1 more

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. HyperpolarizedResearch square · 2026
    Article
  3. Imaging brain energetics to advance metabolic psychiatry.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  4. Review
  5. Review
  6. Clinical Translation of HyperpolarizedAJNR. American journal of neuroradiology · 2025
    Review
  7. Spatial distribution of hyperpolarized [1-Imaging neuroscience (Cambridge, Mass.) · 2025
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Biranavan UthayakumarDepartment of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
Hany SolimanRadiation Oncology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Albert P ChenGE Healthcare, Toronto, Ontario, Canada.
Nadia BragagnoloPhysical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada.ORCID 0000-0002-3399-2267
Nicole I C CappellettoDepartment of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
Ruby EndrePhysical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada.
William J PerksPharmacy, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Nathan MaPharmacy, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Chris HeynRadiology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Kayvan R KeshariDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Charles H CunninghamDepartment of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0001-9636-8130

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI FRANCESCA M GANY · 1985 to 2026
$347.4M
TR&D3: Open-Source Tools for Processing Hyperpolarized MR DataP41EB013598 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Daniel B Vigneron · 2011 to 2026
$19.9M
Leveraging fructose transport to create a privileged substrate to selectively fuel T cellsR01CA248364 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Kayvan R Keshari · 2021 to 2026
$4.3M
Development of large-field-of-view hyperpolarized MRIR01CA237466 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI CUNNINGHAM, CHARLES H., HRICAK, HEDVIG · 2020 to 2024
$3.4M
CIHR PJT-152928NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA237466NCI NIH HHS R01 CA248364NIBIB NIH HHS P41 EB013598NIH HHS R01CA237466
6 · The paper itself

Abstract

purposeTo test the hypothesis that lactate oxidation contributes to the

methodsHealthy human volunteers (N = 6) were scanned twice using hyperpolarized

resultsIncreased

conclusionRadiofrequency saturation of

Indexed as

BicarbonatesMagnetic Resonance ImagingBrainCarbon IsotopesHumansLactic AcidPyruvic AcidBicarbonatesCarbon IsotopesLactic AcidPyruvic Acidbiochemistrybrainneurologicalnormal

Identifiers

PMID38230992
PMCPMC11225103

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.