Evidence map›Paper›PMID 38236385›Full record

ArticleInflammation2024

METTL3 Modulates TXNIP Expression to Affect the Activation of NLRP3 Inflammasome in Hepatic Cells Under Oxygen-Glucose Deprivation/Reperfusion Injury.

Yong Zhang, Jianrui Lv, Jian Bai, Xue Zhang, Gang Wu, Xiaoming Lei, Wei Li, Zhenni Zhang

Abstract read
PubMed Publisher
In one paragraph

Article in Inflammation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yong ZhangAnesthesia Department, the Second Affiliated Hospital of Xi'an Jiaotong University, No. 157, West 5th Road, Xi'an, Shaanxi Province, 710004, China.
Jianrui LvAnesthesia Department, the Second Affiliated Hospital of Xi'an Jiaotong University, No. 157, West 5th Road, Xi'an, Shaanxi Province, 710004, China.
Jian BaiDepartment of General Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Xue ZhangDepartment of General Practice, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Gang WuAnesthesia Department, the Second Affiliated Hospital of Xi'an Jiaotong University, No. 157, West 5th Road, Xi'an, Shaanxi Province, 710004, China.
Xiaoming LeiAnesthesia Department, the Second Affiliated Hospital of Xi'an Jiaotong University, No. 157, West 5th Road, Xi'an, Shaanxi Province, 710004, China.
Wei LiAnesthesia Department, the Second Affiliated Hospital of Xi'an Jiaotong University, No. 157, West 5th Road, Xi'an, Shaanxi Province, 710004, China.
Zhenni ZhangAnesthesia Department, the Second Affiliated Hospital of Xi'an Jiaotong University, No. 157, West 5th Road, Xi'an, Shaanxi Province, 710004, China. jennyzzn@sohu.com.
Second Affiliated Hospital of Xi'an Jiaotong University · CNCapital Medical University · CN

Funding

National Natural Science Foundation of China 82103553Shaanxi Provincial Health Research Fund 2022D005
6 · The paper itself

Abstract

Hepatic ischemia-reperfusion (I/R) injury is still a major risk factor and unsolved problem in hepatic surgery. Methyltransferase-like 3 (METTL3), an important m

Indexed as

GlucoseInflammasomesMethyltransferasesNLR Family, Pyrin Domain-Containing 3 ProteinOxygenReperfusion InjuryAnimalsCarrier ProteinsCell LineHepatocytesLiverMaleMiceMice, Inbred C57BLReactive Oxygen SpeciesThioredoxinsCarrier ProteinsGlucoseInflammasomesMethyltransferasesMettl3 protein, mouseNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mouseOxygenReactive Oxygen SpeciesThioredoxinsTxnip protein, mouseHepatic ischemia/reperfusion injurym6A modificationMETTL3NLRP3 inflammasomeTXNIP

Identifiers

PMID38236385
OpenAlexW4390963904

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.