Evidence map›Paper›PMID 38236409›Full record

ArticleDiabetologia2024

Cost-utility analysis of Dexcom G6 real-time continuous glucose monitoring versus FreeStyle Libre 1 intermittently scanned continuous glucose monitoring in adults with type 1 diabetes in Belgium.

Margaretha M Visser, Astrid Van Muylder, Sara Charleer, John J Isitt, Stéphane Roze, Christophe De Block, Toon Maes, Gerd Vanhaverbeke, Frank Nobels, Bart Keymeulen and 4 more

Registry-linked trialOpen access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Diabetologia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03772600 (Comparing Continuous With Flash Glucose Monitoring in Adults With Type 1 Diabetes), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03772600 nacompletednot on this map

Comparing Continuous With Flash Glucose Monitoring in Adults With Type 1 Diabetes

TypeinterventionalSponsorUniversitaire Ziekenhuizen KU LeuvenRan2019 to 2022Enrolled269ConditionsType 1 Diabetes MellitusArmsDexcom G6 CGM
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Criteria for Personalised Choice of a Continuous Glucose Monitoring System: An Expert Opinion.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Margaretha M VisserDepartment of Endocrinology, University Hospitals Leuven, KU Leuven, Leuven, Belgium.ORCID 0000-0003-0216-4028
Astrid Van MuylderLeuven Institute for Healthcare Policy, KU Leuven, Leuven, Belgium.ORCID 0000-0002-5387-6108
Sara CharleerDepartment of Endocrinology, University Hospitals Leuven, KU Leuven, Leuven, Belgium.
John J IsittVyoo Agency, San Diego, CA, USA.
Stéphane RozeVyoo Agency, Lyon, France.
Christophe De BlockDepartment of Endocrinology-Diabetology-Metabolism, University Hospital Antwerp, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Toon MaesDepartment of Endocrinology, Imeldaziekenhuis Bonheiden, Bonheiden, Belgium.
Gerd VanhaverbekeDepartment of Endocrinology, AZ Groeninge, Kortrijk, Belgium.
Frank NobelsDepartment of Endocrinology, OLV Hospital Aalst, Aalst, Belgium.
Bart KeymeulenAcademic Hospital and Diabetes Research Centre, Vrije Universiteit Brussel, Brussels, Belgium.
Chantal MathieuDepartment of Endocrinology, University Hospitals Leuven, KU Leuven, Leuven, Belgium.
Jeroen LuytenLeuven Institute for Healthcare Policy, KU Leuven, Leuven, Belgium.
Pieter GillardDepartment of Endocrinology, University Hospitals Leuven, KU Leuven, Leuven, Belgium. pieter.gillard@uzleuven.be.ORCID 0000-0001-9111-4561
Nick VerhaegheResearch Institute for Work and Society, KU Leuven, Leuven, Belgium.ORCID 0000-0001-9956-4970
KU Leuven · BEAZ Groeninge · BEGhent University · BEImelda Hospital · BEOnze Lieve Vrouwziekenhuis Hospital · BEUniversity of Antwerp · BEVrije Universiteit Brussel · BE

Funding

Dexcom OUS-2018-011
6 · The paper itself

Abstract

aims/hypothesisThe aim of this study was to assess the long-term cost-effectiveness of Dexcom G6 real-time continuous glucose monitoring (rtCGM) with alert functionality compared with FreeStyle Libre 1 intermittently scanned continuous glucose monitoring (isCGM) without alerts in adults with type 1 diabetes in Belgium.

methodsThe IQVIA CORE Diabetes Model was used to estimate cost-effectiveness. Input data for the simulated baseline cohort were sourced from the randomised ALERTT1 trial (ClinicalTrials.gov. REGISTRATION NO: NCT03772600). The age of the participants was 42.9 ± 14.1 years (mean ± SD), and the baseline HbA

resultsIn the base case, rtCGM dominated isCGM, resulting in lower diabetes-related complication costs and better health outcomes. The associated main drivers favouring rtCGM were lower HbA CONCLUSIONS/

interpretationWhen priced similarly, Dexcom G6 rtCGM with alert functionality has both economic and clinical benefits compared with FreeStyle Libre 1 isCGM without alerts in adults with type 1 diabetes in Belgium, and appears to be a cost-effective glucose monitoring modality. Trial registration ClinicalTrials.gov NCT03772600.

Indexed as

Diabetes Mellitus, Type 1AdultBelgiumBlood GlucoseBlood Glucose Self-MonitoringContinuous Glucose MonitoringCost-Benefit AnalysisHumansHypoglycemic AgentsMiddle AgedBlood GlucoseHypoglycemic AgentsCost-effectivenessCost–utility analysisEconomic evaluationIntermittently scanned continuous glucose monitoringReal-time continuous glucose monitoringType 1 diabetes

Identifiers

PMID38236409
OpenAlexW4390979973

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.