ArticleAmerican journal of respiratory and critical care medicine2024
The Plasma Lipidomic Landscape in Patients with Sepsis due to Community-acquired Pneumonia.
Open access · greenAbstract read
In one paragraph
Article in American journal of respiratory and critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
8.4field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Clinical lipidomics in bacterial sepsis: a systematic review of serum and plasma evaluations.Metabolomics : Official journal of the Metabolomic Society · 2026Pooled it
- Longitudinal multiomic signatures of ARDS and sepsis inflammatory phenotypes identify pathways associated with mortality.The Journal of clinical investigation · 2026Trial
- Endotoxemia and its association with immune and coagulopathy responses in severe community-acquired pneumonia and COVID-19.Intensive care medicine experimental · 2026Article
- Amplified inflammatory and immune responses in viral-associated pulmonary aspergillosis.Frontiers in cellular and infection microbiology · 2026Article
- Thrombomodulin: a potential biomarker for sepsis-associated acute kidney injury resulting from bacterial infections.Frontiers in cellular and infection microbiology · 2026Observational
- Serum lipidome remodeling in viral pneumonia: from pathophysiology to therapeutics.Frontiers in immunology · 2026Review
- Early biomarkers for predicting sepsis-induced shock: insights from inflammatory pathways and immune response.Frontiers in pharmacology · 2026Review
- Gut microbiota and sepsis: mechanisms, clinical correlations, and therapeutic prospects.Frontiers in medicine · 2026Article
- Prognostic value of IL-6, HMGB1, and TLR4 in bronchoalveolar lavage fluid of patients with community-acquired pneumonia.American journal of translational research · 2026Article
- Effect of the gut microbiota-derived tryptophan metabolite indole-3-acetic acid in pneumonia.Nature communications · 2025Observational
- Role of Lipidomics in Respiratory Tract Infections: A Systematic Review of Emerging Evidence.Microorganisms · 2025Review
- High-fat diet obesity exacerbates acute lung injury-induced dysregulation of fatty acid oxidation in alveolar epithelial type 2 cells.American journal of physiology. Lung cellular and molecular physiology · 2025Article
- Reduced phosphatidylcholine and phosphatidylethanolamine levels correlate with inflammatory activation in sepsis-associated encephalopathy.European journal of medical research · 2025Observational
- Multi-Omics and -Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- The flux of energy in critical illness and the obesity paradox.Physiological reviews · 2025Review
- Lipidomic signatures of ventilator-associated pneumonia in COVID-19 ARDS patients: a new frontier for diagnostic biomarkers.Annals of intensive care · 2025Article
- Pulmonary metabolic changes in a rabbit model of Pseudomonas aeruginosa pneumonia: insights from metabolomic analysis.BMC microbiology · 2025Article
- Pneumonia-specific plasma metabolite profiles among patients hospitalised with infection in Southeast Asia.ERJ open research · 2025Article
- Untargeted lipidomics profiling provides novel insights into pediatric patients with sepsis: an exploratory study.Metabolomics : Official journal of the Metabolomic Society · 2025Article
- Integrated Metabolomics and Lipidomics Analysis Reveals the Mechanism Behind the Action of Chiglitazar on the Protection Against Sepsis-Induced Acute Lung Injury.Metabolites · 2025Article
Corrections and comments
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Authors and funding
18 authors at 11 institutions in 6 countries.
Osoul ChouchaneCenter for Experimental and Molecular Medicine.ORCID 0000-0003-1629-8588
Alex R SchuurmanCenter for Experimental and Molecular Medicine.ORCID 0000-0001-9322-1117
Tom D Y ReijndersCenter for Experimental and Molecular Medicine.ORCID 0000-0002-1764-0114
Hessel Peters-SengersCenter for Experimental and Molecular Medicine.ORCID 0000-0003-3145-864X
Joe M ButlerCenter for Experimental and Molecular Medicine.ORCID 0000-0001-6781-6408
Fabrice UhelInstitut National de la Santé et de la Recherche Médicale Unité Mixte de Recherche S1151, Centre National de la Recherche Scientifique Unité Mixte de Recherche S8253, Institut Necker-Enfants Malades, Université Paris Cité, Paris, France.ORCID 0000-0003-4946-8184
Marcus J SchultzDepartment of Intensive Care Medicine.ORCID 0000-0003-3969-7792
Marc J BontenDepartment of Medical Microbiology.
Olaf L CremerDepartment of Intensive Care Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID 0000-0003-4264-1108
Carolyn S CalfeeDepartments of Medicine and Anesthesia, Cardiovascular Research Institute, University of California, San Francisco, California.
Michael A MatthayDepartments of Medicine and Anesthesia, Cardiovascular Research Institute, University of California, San Francisco, California.
Raymond J LangleyDepartment of Pharmacology, University of South Alabama College of Medicine, Mobile, Alabama.ORCID 0000-0001-8849-9325
Narges Alipanah-LechnerDivision of Pulmonary and Critical Care, Department of Medicine, Stanford, California; and.ORCID 0000-0002-8381-5701
Stephen F KingsmoreRady Children's Institute for Genomic Medicine, Rady Children's Hospital, San Diego, California.ORCID 0000-0001-7180-2527
Angela RogersDivision of Pulmonary and Critical Care, Department of Medicine, Stanford, California; and.ORCID 0000-0001-6969-6200
Michel van WeeghelDepartment of Clinical Chemistry and Pediatrics, Laboratory Genetic Metabolic Diseases, Emma Children's Hospital.ORCID 0000-0002-4916-2866
Frédéric M VazDepartment of Clinical Chemistry and Pediatrics, Laboratory Genetic Metabolic Diseases, Emma Children's Hospital.ORCID 0000-0002-9048-1041
Tom van der PollCenter for Experimental and Molecular Medicine.ORCID 0000-0002-9199-5079
Center for Molecular Medicine and Immunology · USAmsterdam UMC Location University of Amsterdam · NLStanford Medicine · USUniversity of California, San Francisco · USChildren’s Institute · USInserm · FRMahidol University · THOffice of Infectious Diseases · USOklahoma State University Center for Health Sciences · USUniversity Medical Center Utrecht · NLUniversity of South Alabama · US
Funding
Precision Medicine in the Acute Respiratory Distress SyndromeR35HL140026 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CALFEE, CAROLYN · 2018 to 2024
$6.8MAard- en Levenswetenschappen, Nederlandse Organisatie voor Wetenschappelijk Onderzoek NACTAR no. 16447Horizon 2020 Framework Programme FAIR 847786Landsteiner Foundation for Blood Transfusion Research LSBR no. 1901NHLBI NIH HHS R35 HL140026
Abstract
PubMed holds no abstract for this paper.
Indexed as
Community-Acquired InfectionsPneumoniaSepsisHumansIntensive Care UnitsLipidomicsLipidsSeverity of Illness IndexLipidscholesterollipidomicsrespiratory failuresepsistriglycerides
Identifiers
What Socratic holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.