Evidence map›Paper›PMID 38243869›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

LINC MIR503HG Controls SC-β Cell Differentiation and Insulin Production by Targeting CDH1 and HES1.

Yang Xu, Susu Mao, Haowen Fan, Jian Wan, Lin Wang, Mingyu Zhang, Shajun Zhu, Jin Yuan, Yuhua Lu, Zhiwei Wang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Molecular Effects of Glucose onBritish journal of biomedical science · 2025
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Yang XuDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, 226001, China.ORCID 0000-0001-9624-9238
Susu MaoKey Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, 226001, China.
Haowen FanDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, 226001, China.
Jian WanDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, 226001, China.
Lin WangDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, 226001, China.
Mingyu ZhangDepartment of Nuclear Medicine, Beijing Friendship Hospital, Affiliated to Capital Medical University, Beijing, 100050, China.
Shajun ZhuDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, 226001, China.
Jin YuanDepartment of Endocrinology and Metabolism, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, 226001, China.
Yuhua LuDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, 226001, China.
Zhiwei WangDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, 226001, China.
Bin YuKey Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, 226001, China.
Zhaoyan JiangCenter of Gallbladder Disease, Shanghai East Hospital, Institute of Gallstone Disease, School of Medicine, Tongji University, Shanghai, 200092, China.
Yan HuangDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, 226001, China.ORCID 0000-0001-5281-0783
Nantong University · CNCapital Medical University · CNDalian Medical University · CNShanghai East Hospital · CN

Funding

China Postdoctoral Science Foundation 2021M690085Clinical Discipline Project of Shanghai Pudong PWYts 2021-06National Natural Science Foundation of China 82001860National Natural Science Foundation of China 82001977National Natural Science Foundation of China 82070654National Natural Science Foundation of China 82272170National Natural Science Foundation of China 82372133
6 · The paper itself

Abstract

Stem cell-derived pancreatic progenitors (SC-PPs), as an unlimited source of SC-derived β (SC-β) cells, offers a robust tool for diabetes treatment in stem cell-based transplantation, disease modeling, and drug screening. Whereas, PDX1

Indexed as

Diabetes MellitusInsulinInsulin-Secreting CellsRNA, Long NoncodingAntigens, CDCadherinsCell DifferentiationHomeodomain ProteinsHumansTrans-ActivatorsTranscription Factor HES-1Transcription FactorsAntigens, CDCadherinsCDH1 protein, humanHES1 protein, humanHomeodomain ProteinsInsulinlong non-coding RNA MIR503HG, humanRNA, Long NoncodingTrans-ActivatorsTranscription Factor HES-1Transcription Factorsdifferentiationhuman pluripotent stem cellslncRNApancreatic progenitorsscRNA‐seq

Identifiers

PMID38243869
PMCPMC10987150
OpenAlexW4391050962

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.