Evidence map›Paper›PMID 38244153›Full record

ArticleJournal of assisted reproduction and genetics2024

The risk of perinatal and cardiometabolic complications in pregnancies conceived by medically assisted reproduction.

Dovile Vilda, Elizabeth F Sutton, Venkata Sai Sahithi Kothamasu, Paul R Clisham, Cecilia T Gambala, Emily W Harville

Open access · hybridAbstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Dovile VildaDepartment of Social, Behavioral, and Population Sciences, Mary Amelia Center for Women's Health Equity Research, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA. dvilda@tulane.edu.ORCID http://orcid.org/0000-0002-1763-3432
Elizabeth F SuttonWoman's Hospital, Baton Rouge, LA, USA.
Venkata Sai Sahithi KothamasuTulane University School of Medicine, New Orleans, LA, USA.
Paul R ClishamTulane University School of Medicine, New Orleans, LA, USA.
Cecilia T GambalaDepartment of Obstetrics and Gynecology, Tulane University School of Medicine, New Orleans, LA, USA.
Emily W HarvilleDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.
Tulane University · USWoman's Hospital · US

Funding

Tulane Building Interdisciplinary Research Careers in Women's Health (BIRCWH)K12HD043451 · NICHD · TULANE UNIVERSITY OF LOUISIANA · PI KROUSEL-WOOD, MARIE · 2002 to 2023
$9.9M
Building Interdisciplinary Research Careers in Women's HealthK12AR084224 · NIAMS · TULANE UNIVERSITY OF LOUISIANA · PI Marie Krousel-Wood · 2024 to 2026
$1.6M
NIAMS NIH HHS K12 AR084224NIAMS NIH HHS K12HD043451NICHD NIH HHS K12 HD043451
6 · The paper itself

Abstract

purposeTo examine the impact of medically assisted fertility treatments on the risk of developing perinatal and cardiometabolic complications during pregnancy and in-hospital deliveries.

methodsWe conducted a retrospective cohort study using medical health records of deliveries occurring in 2016-2022 at a women's specialty hospital in a southern state of the Unites States (US). Pregnancies achieved using medically assisted reproductive (MAR) techniques were compared with unassisted pregnancies using propensity score matching (PSM), based on demographic, preexisting health, and reproductive factors. Study outcomes included cesarean delivery, gestational diabetes mellitus (GDM), hypertensive disorders of pregnancy (HDP), delivery complications, and postpartum readmission. We used Poisson regression with robust standard errors to generate risk ratios (RRs) and 95% confidence intervals (CIs) for all study outcomes.

resultsAmong 57,354 deliveries, 586 (1.02%) pregnancies were achieved using MAR and 56,768 (98.98%) were unassisted ("non-MAR"). Compared to the non-MAR group, MAR pregnancies had significantly higher prevalence of all study outcomes, including GDM (15.9% vs. 11.2%, p < 0.001), HDP (28.2% vs. 21.1%, p < 0.001), cesarean delivery (56.1% vs. 34.6%, p < 0.001), delivery complications (10.9% vs. 6.8%, p = 0.03), and postpartum readmission (4.3% vs. 2.7%, p = 0.02). In a PSM sample of 584 MAR and 1,727 unassisted pregnancies, MAR was associated with an increased risk of cesarean delivery (RR = 1.11, 95% CI = 1.01-1.22); whereas IVF was associated with an increased risk of cesarean delivery (RR = 1.15, 95% CI = 1.03-1.28) and delivery complications (RR = 1.44, 95% CI = 1.04-2.01).

conclusionsWomen who conceived with MAR were at increased risk of cesarean deliveries, and those who conceived with IVF were additionally at risk of delivery complications.

Indexed as

Cardiovascular DiseasesDiabetes, GestationalPre-EclampsiaFemaleFertilityFertilizationHumansPregnancyPregnancy OutcomeRetrospective StudiesCardiometabolic complicationsElectronic medical recordsMedically assisted reproductionPerinatalPropensity score matching

Identifiers

PMID38244153
PMCPMC10957823
OpenAlexW4391053013

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.