Evidence map›Paper›PMID 38248750›Full record

ArticleJournal of personalized medicine2023

Association between the Number of Days/Week of Different Levels of Physical Activity and Chronic Pain in People of Different Races: A Mendelian Randomization Study.

Sumei Luo, Minjing Yang, Haojun Yang, Qulian Guo, Yunjiao Wang, E Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 65% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sumei LuoDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008, China.
Minjing YangDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008, China.
Haojun YangDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008, China.
Qulian GuoDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008, China.
Yunjiao WangDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008, China.
E WangDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008, China.ORCID 0000-0001-9463-9769
Central South University · CN

Funding

National Key Research and Development Project of China 2020YFC2005300
6 · The paper itself

Abstract

objectiveRegular physical activity is beneficial for health, but the effect of the number of days/week of physical activity on chronic pain (CP) remains unclear, so we used a two-sample Mendelian randomization (MR) analysis to explore the relationship between the number of days/weeks of different levels of physical activity and chronic pain in people of different races.

methodsWe obtained summary data from genome-wide association studies (GWASs) on the number of days/week of physical activity and multisite chronic pain in European, South Asian, East Asian, Middle Eastern, and African American populations. The single-nucleotide polymorphisms (SNPs) of the exposed data were visualized with a Manhattan plot via the R program. MR analysis was performed by the MR-Base platform.

resultsThe results indicated that a higher number of days/week with ≥10 min of walking protects against CP in African American and Afro-Caribbean populations (inverse-variance weighting, IVW

conclusionsA higher number of days/week of moderate and vigorous physical activity increased the risk of CP in Europeans; however, a higher number of days/week of walking and vigorous physical activity may protect against CP in African American and Afro-Caribbean individuals.

Indexed as

chronic paingenome-wide association studyMendelian randomizationphysical activityrace

Identifiers

PMID38248750
PMCPMC10821097
OpenAlexW4390437171

What Socratic holds

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LicenceCC BY
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Registered trials

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