Evidence mapPaperPMID 38249939Full record

ArticleWomen's health reports (New Rochelle, N.Y.)2024

Drug Exposure During Pregnancy: A Case-Control Study from a Primary Care Database.

Ainhoa Gomez-Lumbreras, Marta Leston Vazquez, Carles Vilaplana-Carnerero, Oriol Prat-Vallverdu, Cristina Vedia, Rosa Morros, Maria Giner-Soriano

Abstract read
In one paragraph

Article in Women's health reports (New Rochelle, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Migraine and Pregnancy.Life (Basel, Switzerland) · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ainhoa Gomez-LumbrerasDepartment of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City, Utah, USA.
Marta Leston VazquezÀrea del Medicament i Servei de Farmàcia, Gerència d'Atenció Primària Barcelona Ciutat, Institut Català de la Salut, Barcelona, Spain.
Carles Vilaplana-CarnereroUniversitat Autònoma de Barcelona, Bellaterra (Cerdanyola del Vallès), Spain.
Oriol Prat-VallverduFundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain.
Cristina VediaUniversitat Autònoma de Barcelona, Bellaterra (Cerdanyola del Vallès), Spain.
Rosa MorrosUniversitat Autònoma de Barcelona, Bellaterra (Cerdanyola del Vallès), Spain.
Maria Giner-SorianoUniversitat Autònoma de Barcelona, Bellaterra (Cerdanyola del Vallès), Spain.ORCID https://orcid.org/0000-0003-3750-9233

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Drug exposure during pregnancy is frequent, even more during first trimester as pregnant women might not be aware of their condition. We used available electronic health records (EHRs) to describe the use of medications during the first trimester in pregnant women and to compare drug exposure between those women who had an abortion (either elective or spontaneous) compared to those who had live births. Materials and Methods: Case-control study of abortions, either elective or spontaneous (cases), and live birth pregnancies (controls) in Sistema d'Informació per al Desenvolupament de la Investigació en Atenció Primària (Catalan Primary Health electronic health records) from 2012 to 2020. Exposure to drugs during first trimester of pregnancy was considered to estimate the association with abortion by conditional logistic regression and adjusted by health conditions and other drugs exposure. Results: Sixty thousand three hundred fifty episodes of abortions were matched to 118,085 live birth pregnancy episodes. Cases had higher rates of alcohol intake (9.9% vs. 7.2%, Conclusions: These high rates of drug exposures during the first trimester of pregnancy highlights the relevance of informed prescription to women with childbearing potential.

Indexed as

abnormalities, drug-inducedabortion, inducedabortion, spontaneouscase-control studieslabor, obstetriclive birthmaternal-fetal exchange

Identifiers

PMID38249939
PMCPMC10798141

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.