Evidence map›Paper›PMID 38255664›Full record

ArticleLife (Basel, Switzerland)2023

Biological Activities of Molecules Derived from

Giulia Marrone, Silvia Urciuoli, Eleonora Candi, Roberta Bernini, Gianluca Vanni, Claudia Masci, Cristina Guerriero, Mara Mancini, Antonino De Lorenzo, Pamela Vignolini and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Lifestyle and Environment Aspects Challenging Kidney Health.Kidney & blood pressure research · 2026
    Review
  4. Article
  5. Saffron (Nutrients · 2024
    Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Giulia MarroneDepartment of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-5854-2086
Silvia UrciuoliPHYTOLAB (Pharmaceutical, Cosmetic, Food Supplement, Technology and Analysis)-DiSIA, University of Florence, 50019 Florence, Italy.
Eleonora CandiDepartment of Experimental Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.
Roberta BerniniDepartment of Agriculture and Forest Sciences (DAFNE), University of Tuscia, Via San Camillo de Lellis, 01100 Viterbo, Italy.ORCID 0000-0002-2548-3876
Gianluca VanniBreast Unit, Department of Surgical Science, Policlinico Tor Vergata University, 00133 Rome, Italy.
Claudia MasciDepartment of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.
Cristina GuerrieroDepartment of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-6104-6059
Mara ManciniIstituto Dermatopatico Dell'Immacolata-IDI, Istituto di Ricovero e Cura a Carattere Scientifico-IRCCS, Via Monti di Creta 104, 00166 Rome, Italy.ORCID 0000-0001-5173-4854
Antonino De LorenzoSection of Clinical Nutrition and Nutrigenomic, Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0001-6524-4493
Pamela VignoliniPHYTOLAB (Pharmaceutical, Cosmetic, Food Supplement, Technology and Analysis)-DiSIA, University of Florence, 50019 Florence, Italy.ORCID 0000-0002-9500-7971
Annalisa NoceDepartment of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0003-1310-3730
University of Rome Tor Vergata · ITUniversity of Florence · ITIstituto Dermopatico dell'Immacolata · ITPoliclinico Tor Vergata · ITUniversità degli Studi della Tuscia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExtra virgin olive oil is a typical food of the Mediterranean area, obtained by pressing MATERIALS AND

methodsWe selected

resultsThis study showed that all the tested extracts can significantly inhibit cellular growth at 50 µM but the reduced proliferation is not related to an increase in cellular apoptosis. Instead, the same analysis performed by using extracts at 100 µM reveals that they can inhibit cellular growth, further inducing cellular apoptosis.

conclusionsThe results on the HEK-293E cells confirmed the antiproliferative and proapoptotic actions of active compounds from an

Indexed as

chronic degenerative non-communicable diseaseschronic kidney diseaseHEK-293EhydroxytyrosolIncuCyteMediterranean dietOlea europaea L.oleuropein

Identifiers

PMID38255664
PMCPMC10820526
OpenAlexW4390338845

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.