Evidence map›Paper›PMID 38257299›Full record

ArticleMolecules (Basel, Switzerland)2024

Novel Flurbiprofen Derivatives as Antioxidant and Anti-Inflammatory Agents: Synthesis, In Silico, and In Vitro Biological Evaluation.

Iliyan Ivanov, Stanimir Manolov, Dimitar Bojilov, Gabriel Marc, Diyana Dimitrova, Smaranda Oniga, Ovidiu Oniga, Paraskev Nedialkov, Maria Stoyanova

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Iliyan IvanovDepartment of Organic Chemistry, Faculty of Chemistry, University of Plovdiv, 24 "Tsar Assen" Street., 4000 Plovdiv, Bulgaria.ORCID 0000-0002-4662-3735
Stanimir ManolovDepartment of Organic Chemistry, Faculty of Chemistry, University of Plovdiv, 24 "Tsar Assen" Street., 4000 Plovdiv, Bulgaria.ORCID 0000-0002-0314-6553
Dimitar BojilovDepartment of Organic Chemistry, Faculty of Chemistry, University of Plovdiv, 24 "Tsar Assen" Street., 4000 Plovdiv, Bulgaria.ORCID 0000-0001-6569-8348
Gabriel MarcDepartment of Pharmaceutical Chemistry, "Iuliu Hațieganu" University of Medicine and Pharmacy, 41 Victor Babeș Street, 400012 Cluj-Napoca, Romania.ORCID 0000-0001-9397-0388
Diyana DimitrovaDepartment of Organic Chemistry, Faculty of Chemistry, University of Plovdiv, 24 "Tsar Assen" Street., 4000 Plovdiv, Bulgaria.ORCID 0009-0009-2623-0043
Smaranda OnigaDepartment of Therapeutic Chemistry, "Iuliu Hațieganu" University of Medicine and Pharmacy, 12 Ion Creangă Street, 400010 Cluj-Napoca, Romania.ORCID 0000-0002-0297-7697
Ovidiu OnigaDepartment of Pharmaceutical Chemistry, "Iuliu Hațieganu" University of Medicine and Pharmacy, 41 Victor Babeș Street, 400012 Cluj-Napoca, Romania.
Paraskev NedialkovDepartment of Pharmacognosy, Faculty of Pharmacy, Medical University of Sofia, 2 Dunav Street, 1000 Sofia, Bulgaria.ORCID 0000-0001-5640-6120
Maria StoyanovaDepartment of Organic Chemistry, Faculty of Chemistry, University of Plovdiv, 24 "Tsar Assen" Street., 4000 Plovdiv, Bulgaria.ORCID 0000-0002-1687-0823
Plovdiv University · BGIuliu Hațieganu University of Medicine and Pharmacy · ROMedical University of Sofia · BG

Funding

Plovdiv University ΦΠ23-XΦ-005Plovdiv University Д23-2-ХФ-013
6 · The paper itself

Abstract

In this study, we present the synthesis of five novel compounds by combining flurbiprofen with various substituted 2-phenethylamines. The synthesized derivatives underwent comprehensive characterization using techniques such as

Indexed as

FlurbiprofenAnti-Inflammatory AgentsAntioxidantsHumansMolecular Docking SimulationRadiopharmaceuticalsAnti-Inflammatory AgentsAntioxidantsFlurbiprofenRadiopharmaceuticals2-phenethylaminesamidesflurbiprofenin silicoin vitrolipophilicitymolecular dockingsynthesistoxicity

Identifiers

PMID38257299
PMCPMC10818523
OpenAlexW4390831202

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.