Evidence map›Paper›PMID 38258133›Full record

ArticlePharmaceutics2024

Biomolecules to Biomarkers? U87MG Marker Evaluation on the Path towards Glioblastoma Multiforme Pathogenesis.

Markéta Pokorná, Viera Kútna, Saak V Ovsepian, Radoslav Matěj, Marie Černá, Valerie Bríd O'Leary

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Markéta PokornáDepartment of Medical Genetics, Third Faculty of Medicine, Charles University, Ruská 87, Vinohrady, 10000 Prague, Czech Republic.
Viera KútnaDepartment of Experimental Neurobiology, National Institute of Mental Health, Topolová 748, 25067 Klecany, Czech Republic.
Saak V OvsepianFaculty of Engineering and Science, University of Greenwich London, Chatham Maritime, Kent ME4 4TB, UK.ORCID 0000-0002-9522-4159
Radoslav MatějDepartment of Pathology, Third Faculty of Medicine, Charles University, Ruská 87, Vinohrady, 10000 Prague, Czech Republic.ORCID 0000-0002-6152-6343
Marie ČernáDepartment of Medical Genetics, Third Faculty of Medicine, Charles University, Ruská 87, Vinohrady, 10000 Prague, Czech Republic.ORCID 0000-0002-1208-5588
Valerie Bríd O'LearyDepartment of Medical Genetics, Third Faculty of Medicine, Charles University, Ruská 87, Vinohrady, 10000 Prague, Czech Republic.ORCID 0000-0003-1171-9830
Charles University · CZNational Institute of Mental Health · CZUniversity of Greenwich · GB

Funding

Charles University COOPERATIO: the scientific project "Medical Diagnostics and Basic Medical Sciences" (in the field "Medical Genetics"), grant number 207036Charles University neurology SVV grant 260648/SVV/2023: Research of drug addiction and neuropsychiatric diseases - from the basic research to the clinical practice.
6 · The paper itself

Abstract

The heterogeneity of the glioma subtype glioblastoma multiforme (GBM) challenges effective neuropathological treatment. The reliance on in vitro studies and xenografted animal models to simulate human GBM has proven ineffective. Currently, a dearth of knowledge exists regarding the applicability of cell line biomolecules to the realm of GBM pathogenesis. Our study's objectives were to address this preclinical issue and assess prominin-1, ICAM-1,

Indexed as

BiomarkerEker ratsGAS5GBMGliomaICAM-1lncRNAPARTICLEprominin-1U87MG

Identifiers

PMID38258133
PMCPMC10818292
OpenAlexW4390985638

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.