Evidence map›Paper›PMID 38260427›Full record

ArticlebioRxiv : the preprint server for biology2024

Environmental and molecular control of tissue-specific ionocyte differentiation in zebrafish.

Julia Peloggia, Mark E Lush, Ya-Yin Tsai, Christopher Wood, Tatjana Piotrowski

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Julia PeloggiaStowers Institute for Medical Research, Kansas City, MO 64110, USA.ORCID 0000-0003-4635-3920
Mark E LushStowers Institute for Medical Research, Kansas City, MO 64110, USA.ORCID 0000-0002-2128-524X
Ya-Yin TsaiStowers Institute for Medical Research, Kansas City, MO 64110, USA.ORCID 0000-0002-9152-7646
Christopher WoodStowers Institute for Medical Research, Kansas City, MO 64110, USA.
Tatjana PiotrowskiStowers Institute for Medical Research, Kansas City, MO 64110, USA.ORCID 0000-0001-8098-2574
Stowers Institute for Medical Research · US

Funding

Zebrafish Sensory Hair Cell RegenerationR01DC015488 · NIDCD · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI Tatjana Piotrowski · 2017 to 2026
$2.9M
NIDCD NIH HHS R01 DC015488
6 · The paper itself

Abstract

Organisms adjust their physiology to cope with environmental fluctuations and maintain fitness. These adaptations occur via genetic changes over multiple generations or through acclimation, a set of reversible phenotypic changes that confer resilience to the individual. Aquatic organisms are subject to dramatic seasonal fluctuations in water salinity, which can affect the function of lateral line mechanosensory hair cells. To maintain hair cell function when salinity decreases, ion-regulating cells, Neuromast-associated ionocytes (Nm ionocytes), increase in number and invade lateral line neuromasts. How environmental changes trigger this adaptive differentiation of Nm ionocytes and how these cells are specified is still unknown. Here, we identify Nm ionocyte progenitors as

Indexed as

acclimationion homeostasisionocyteslateral lineneuromastsNotch pathwayplasticitysensory hair cellzebrafish

Identifiers

PMID38260427
PMCPMC10802608
OpenAlexW4390839330

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.