In one paragraphArticle in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
17 authors.
Christian CoffmanDivision of Biostatistics, University of Minnesota, 100 Church Street SE, Minneapolis, 55455-0213, MN, USA.ORCID 0000-0002-5524-864X Eric FeczkoDepartment of Pediatrics, University of Minnesota, 100 Church Street SE, Minneapolis, 55455-0213, MN, USA.ORCID 0000-0003-1337-5517 Bart LarsenDepartment of Pediatrics, University of Minnesota, 100 Church Street SE, Minneapolis, 55455-0213, MN, USA.ORCID 0000-0001-7896-4342 Brenden Tervo-ClemmensDepartment of Psychiatry & Behavioral Sciences, University of Minnesota, 100 Church Street SE, Minneapolis, 55455-0213, MN, USA.ORCID 0000-0002-9557-1126 Gregory ConanMasonic Institue for the Devloping Brain, University of Minnesota, 2025 East River Parkway, Minneapolis, 55414, MN, USA.ORCID 0000-0002-3758-5562 Jacob T LundquistMasonic Institue for the Devloping Brain, University of Minnesota, 2025 East River Parkway, Minneapolis, 55414, MN, USA.ORCID 0000-0001-9573-1954 Audrey HoughtonMasonic Institue for the Devloping Brain, University of Minnesota, 2025 East River Parkway, Minneapolis, 55414, MN, USA.ORCID 0000-0001-9426-7969 Lucille A MooreMasonic Institue for the Devloping Brain, University of Minnesota, 2025 East River Parkway, Minneapolis, 55414, MN, USA.ORCID 0000-0002-7665-2713 Kimberly WeldonMasonic Institue for the Devloping Brain, University of Minnesota, 2025 East River Parkway, Minneapolis, 55414, MN, USA.ORCID 0000-0003-4349-9916 Rae McCollumMasonic Institue for the Devloping Brain, University of Minnesota, 2025 East River Parkway, Minneapolis, 55414, MN, USA.ORCID 0009-0002-3730-9995 Anders J PerroneMasonic Institue for the Devloping Brain, University of Minnesota, 2025 East River Parkway, Minneapolis, 55414, MN, USA.ORCID 0000-0003-4376-8047 Begim FayzullobekovaMasonic Institue for the Devloping Brain, University of Minnesota, 2025 East River Parkway, Minneapolis, 55414, MN, USA.ORCID 0009-0000-8014-4108 Thomas J MadisonMasonic Institue for the Devloping Brain, University of Minnesota, 2025 East River Parkway, Minneapolis, 55414, MN, USA.ORCID 0000-0003-3030-6580 Eric EarlMasonic Institue for the Devloping Brain, University of Minnesota, 2025 East River Parkway, Minneapolis, 55414, MN, USA.ORCID 0000-0001-5512-0083 Oscar Miranda DominguezDepartment of Pediatrics, University of Minnesota, 100 Church Street SE, Minneapolis, 55455-0213, MN, USA.ORCID 0000-0002-3622-0166 Damien A FairDepartment of Pediatrics, University of Minnesota, 100 Church Street SE, Minneapolis, 55455-0213, MN, USA.ORCID 0000-0001-8602-393X Saonli BasuDivision of Biostatistics, University of Minnesota, 100 Church Street SE, Minneapolis, 55455-0213, MN, USA.
Funding
Biostatistics in Genetics and Genomics Training ProgramT32GM132063 · NIGMS · UNIVERSITY OF MINNESOTA · PI BASU, SAONLI, PAN, WEI · 2020 to 2024
$1.3MNIGMS NIH HHS T32 GM132063
6 · The paper itselfAbstract
Heritability of regional subcortical brain volumes (rSBVs) describes the role of genetics in middle and inner brain development. rSBVs are highly heritable in adults but are not characterized well in adolescents. The Adolescent Brain Cognitive Development study (ABCD), taken over 22 US sites, provides data to characterize the heritability of subcortical structures in adolescence. In ABCD, site-specific effects co-occur with genetic effects which can bias heritability estimates. Existing methods adjusting for site effects require additional steps to adjust for site effects and can lead to inconsistent estimation. We propose a random-effect model-based method of moments approach that is a single step estimator and is a theoretically consistent estimator even when sites are imbalanced and performs well under simulations. We compare methods on rSBVs from ABCD. The proposed approach yielded heritability estimates similar to previous results derived from single-site studies. The cerebellum cortex and hippocampus were the most heritable regions (>
Indexed as
ABCDfMRIheritabilitySNP
Identifiers
PMID38260520
PMCPMC10802572
What Socratic holds
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