Evidence map›Paper›PMID 38260608›Full record

ArticlebioRxiv : the preprint server for biology2024

Plural molecular and cellular mechanisms of pore domain

Timothy J Abreo, Emma C Thompson, Anuraag Madabushi, Heun Soh, Nissi Varghese, Carlos G Vanoye, Kristen Springer, Kristen L Park, Jim Johnson, Scotty Sims and 15 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors at 7 institutions in 3 countries.

Timothy J AbreoDepartment of Neurology, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0001-5675-7932
Emma C ThompsonDepartment of Neurology, Baylor College of Medicine, Houston, TX, USA.
Anuraag MadabushiDepartment of Neurology, Baylor College of Medicine, Houston, TX, USA.
Heun SohDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT, USA.
Nissi VargheseDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT, USA.
Carlos G VanoyeDepartment of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID 0000-0002-4935-1122
Kristen SpringerDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT, USA.
Kristen L ParkDepartment of Pediatrics, Childrens Colorado, University of Colorado, Aurora, CO, USA.ORCID 0000-0001-5527-3047
Jim JohnsonKCNQ2 Cure Alliance, Denver, CO, USA.
Scotty SimsKCNQ2 Cure Alliance, Denver, CO, USA.
Zhigang JiDepartment of Neurology, Baylor College of Medicine, Houston, TX, USA.
Ana G ChavezDepartment of Neurology, Baylor College of Medicine, Houston, TX, USA.
Miranda J JankovicDepartment of Neurology, Baylor College of Medicine, Houston, TX, USA.
Bereket HabteDepartment of Pediatrics, Childrens Colorado, University of Colorado, Aurora, CO, USA.
Aamir R ZuberiThe Rare Disease Translational Center & Technology Evaluation and Development, The Jackson Laboratory, Bar Harbor, ME, USA.
Cathleen LutzThe Rare Disease Translational Center & Technology Evaluation and Development, The Jackson Laboratory, Bar Harbor, ME, USA.
Zhao WangDepartment of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0003-4897-9986
Vaishnav KrishnanDepartment of Neurology, Baylor College of Medicine, Houston, TX, USA.
Lisa DudlerCenter for Human Genetics Tübingen, Tübingen, Germany.
Stephanie Einsele-ScholzCenter for Human Genetics Tübingen, Tübingen, Germany.
Jeffrey L NoebelsDepartment of Neurology, Baylor College of Medicine, Houston, TX, USA.
Alfred L GeorgeDepartment of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID 0000-0002-3993-966X
Atul MaheshwariDepartment of Neurology, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0003-3045-7901
Anastasios V TzingounisDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT, USA.
Edward C CooperDepartment of Neurology, Baylor College of Medicine, Houston, TX, USA.
Baylor College of Medicine · USUniversity of Connecticut · USCenter for Human Genetics · USCURE International UK · GBJackson Laboratory · USNorthwestern University · USUniversity of Colorado System · US

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Suzanne AW Fuqua · 2007 to 2026
$73.9M
Shared Resource ManagementP30CA034196 · NCI · JACKSON LABORATORY · PI Paul Robson · 1985 to 2026
$61.9M
Project 3 - Development and investigation of murine models of channelopathy-associated epilepsyU54NS108874 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GEORGE, ALFRED L. · 2018 to 2022
$12.1M
The Jackson Laboratory Center for Precision Genetics: From New Models to Novel TherapeuticsU54OD020351 · OD · JACKSON LABORATORY · PI NISHINA, PATSY M · 2015 to 2019
$10.2M
Preclinical and Clincial OutcomesP50HD103555 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI Sandesh Chakravarthy Sreenath Nagamani, David Loren Nelson · 2020 to 2026
$9.9M
PLASTICITY IN DEVELOPING EPILEPTIC BRAINR01NS029709 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI NOEBELS, JEFFREY · 1991 to 2025
$9.1M
Role of KCNQ2 Channels in Control of BreathingR01HL137094 · NHLBI · UNIVERSITY OF CONNECTICUT STORRS · PI MULKEY, DANIEL K, TZINGOUNIS, ANASTASIOS · 2018 to 2025
$4.1M
Mechanisms of benign neonatal familial convulsionsR01NS049119 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI COOPER, EDWARD C · 2005 to 2017
$3.8M
KCNQ2/3 channels and interneuron physiologyR01NS101596 · NINDS · UNIVERSITY OF CONNECTICUT STORRS · PI TZINGOUNIS, ANASTASIOS · 2017 to 2021
$1.7M
Molecular mechanism of Androgen Receptor mediated transcriptionR01GM143380 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI WANG, ZHAO · 2021 to 2025
$1.7M
Investigation of the Cellular and Molecular Mechanisms of Thrombocyte Integrin SignalingR01HL162842 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI WANG, ZHAO · 2022 to 2025
$1.6M
UNRAVELLING THE MECHANISMS OF EPILEPSY-DEPRESSION COMORBIDITY IN A GENETIC MOUSE MODEL OF TEMPORAL LOBE EPILEPSYK08NS110924 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI KRISHNAN, VAISHNAV · 2019 to 2023
$960k
NCI NIH HHS P30 CA034196NCI NIH HHS P30 CA125123NHLBI NIH HHS R01 HL137094NHLBI NIH HHS R01 HL162842NICHD NIH HHS P50 HD103555NIGMS NIH HHS R01 GM143380NIH HHS S10 OD026804NIH HHS U54 OD020351NIMH NIH HHS R56 MH126953NINDS NIH HHS K08 NS096029NINDS NIH HHS K08 NS110924NINDS NIH HHS R01 NS029709NINDS NIH HHS R01 NS049119NINDS NIH HHS R01 NS101596NINDS NIH HHS U54 NS108874
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID38260608
PMCPMC10802467
OpenAlexW4390656920

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.