Evidence map›Paper›PMID 38264149›Full record

ArticleERJ open research2024

Safety, feasibility and effectiveness of the remotely delivered Pulmonary Hypertension and Home-Based (PHAHB) physical activity intervention.

Ciara McCormack, Brona Kehoe, Sarah Cullivan, Noel McCaffrey, Sean Gaine, Brian McCullagh, Andrew McCarren, Sarah J Hardcastle, Niall M Moyna

Registry-linked trialAbstract read
In one paragraph

Article in ERJ open research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07366879 (Randomised Controlled Trial of Exercise Intervention as an Adjunct to Medical Therapy in Newly Diagnosed Patients With Pulmonary Arterial Hypertension), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07366879 narecruitingnot on this mapstarted 2026, after this paper: background citation

Randomised Controlled Trial of Exercise Intervention as an Adjunct to Medical Therapy in Newly Diagnosed Patients With Pulmonary Arterial Hypertension

TypeinterventionalSponsorGolden Jubilee National HospitalRan2026 to 2028Enrolled40ConditionsPulmonary Arterial HypertensionArmsHome-based, remotely delivered, supervised Exercise programme
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Effectiveness and safety of home-basedEuropean respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ciara McCormackSchool of Health and Human Performance, Dublin City University, Dublin, Ireland.ORCID https://orcid.org/0000-0003-4508-5522
Brona KehoeDepartment of Sport and Exercise Science, Waterford Institute of Technology, Waterford City, Ireland.
Sarah CullivanNational Pulmonary Hypertension Unit, Mater Misericordiae University Hospital, Dublin, Ireland.ORCID https://orcid.org/0000-0003-4831-2268
Noel McCaffreyExWell Medical, Dublin, Ireland.
Sean GaineNational Pulmonary Hypertension Unit, Mater Misericordiae University Hospital, Dublin, Ireland.
Brian McCullaghNational Pulmonary Hypertension Unit, Mater Misericordiae University Hospital, Dublin, Ireland.
Andrew McCarrenInsight Centre for Data Analytics and the School of Computing, Dublin City University, Dublin, Ireland.
Sarah J HardcastleDepartment of Sport and Physical Activity, Sheffield Hallam University, Sheffield, UK.ORCID https://orcid.org/0000-0001-8378-3781
Niall M MoynaSchool of Health and Human Performance, Dublin City University, Dublin, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pulmonary hypertension (PH) is a heterogeneous condition, associated with a high symptom burden and a substantial loss of exercise capacity. Despite prior safety concerns regarding physical exertion, exercise training as a supportive therapy is now recommended for PH patients. Currently, most programmes are hospital-based, which limits accessibility. There is a need to provide alternative approaches for physical activity engagement for PH patients. The aim of this research was to develop, implement and evaluate the safety, feasibility and effectiveness of home-based physical activity intervention for PH. Methods: An entirely remotely delivered home-based physical activity intervention underpinned by behaviour change theory and informed by end-users, was assessed using a single-arm feasibility study design. Participants (n=19; 80% female) with a mean±sd age of 49.9±15.9 years with a diagnosis of PH undertook a 10-week, home-based physical activity intervention with induction training, support materials, telecommunication support, health coaching, exercise training and assessments, all remotely delivered. Training involved respiratory training along with a combination of aerobic and resistance exercises. Results: The intervention was deemed safe as no adverse events were reported. A high level of feasibility was demonstrated as the protocol was implemented as intended, sustained a high level of engagement and adherence and was well accepted by participants in terms of enjoyment and utility. There was a significant improvement in functional capacity, physical activity, exercise self-efficacy and quality of life, between baseline and post-training. Conclusion: The study demonstrates that an entirely remotely delivered home-based physical activity programme is safe, feasible and effective in improving functional capacity, physical activity and quality of life in PH patients.

Identifiers

PMID38264149
PMCPMC10805266

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.