Evidence map›Paper›PMID 38269231›Full record

ReviewCureus2023

Cardio-Oncology: Managing Cardiovascular Complications of Cancer Therapies.

Roshan Sharma, Jyoti Kashyap, Olusegun A Olanrewaju, Abdul Jabbar, Fnu Someshwar, Hira Saeed, Giustino Varrassi, Hafiza Amna Qadeer, Satish Kumar, Asfand Yar Cheema and 3 more

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 11 citations in OpenAlex.

  1. Mitochondrial Imaging Detects Early Cardiac Changes Following Cancer Immunotherapy.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026
    Article
  2. The burden of cardiovascular disease in prostate cancer: prevalence, pathophysiology, and implications for integrated care.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Overview of Oncology: Drug-Induced Cardiac Toxicity.Medicina (Kaunas, Lithuania) · 2025
    Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 4 countries.

Roshan SharmaMedicine, Sanjay Gandhi Memorial Hospital, Delhi, IND.
Jyoti KashyapMedicine, Sri Balaji Action Medical Institute, Delhi, IND.
Olusegun A OlanrewajuPure and Applied Biology, Ladoke Akintola University of Technology, Ogbomoso, NGA.
Abdul JabbarMedicine, Jinnah Sindh Medical University, Karachi, PAK.
Fnu SomeshwarMedicine, Liaquat National Hospital and Medical College, Karachi, PAK.
Hira SaeedMedicine, Federal Medical College, Islamabad, PAK.
Giustino VarrassiPain Medicine, Paolo Procacci Foundation, Rome, ITA.
Hafiza Amna QadeerMedicine, Foundation University Medical College, Islamabad, PAK.
Satish KumarMedicine, Shaheed Mohtarma Benazir Bhutto Medical College, Karachi, PAK.
Asfand Yar CheemaMedicine, Services Hospital Lahore, Lahore, PAK.
Mahima KhatriInternal Medicine/Cardiology, Dow University of Health Sciences, Karachi, PAK.
Maha WazirMedicine, Khyber Teaching Hospital, Peshawar, PAK.
Farhan UllahInternal Medicine, Khyber Teaching Hospital, Peshawar, PAK.
Fondazione Roma · ITFoundation University Medical College · PKJinnah Sindh Medical University · PKKhyber Teaching Hospital · PKLadoke Akintola University of Technology · NGLiaquat National Hospital · PKServices Hospital · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This narrative review explores the complex relationship between cancer medicines and cardiovascular health in the junction of oncology and cardiology, known as cardio-oncology. The study examines the historical development of cancer treatments and highlights the growing importance of cardiovascular problems in patient care. This text delves into the topic of cardiotoxicity, examining both conventional chemotherapeutic drugs like anthracyclines and more recent tyrosine kinase and immune checkpoint inhibitors. The complex molecular and cellular mechanisms that control cardiovascular problems are explained, including an understanding of how genetic predisposition influences an individual's sensitivity. The narrative expands into the crucial realm of risk stratification and evaluation, revealing advanced instruments for identifying cardiovascular risk in cancer patients. The importance of non-invasive imaging methods and biomarkers in early detection and continuous monitoring is emphasized. The prioritization of preventive tactics emphasizes the need to take proactive measures incorporating therapies to protect the heart throughout cancer treatment. It also highlights the significance of making lifestyle improvements to reduce risk factors. The narrative emphasizes the changing collaborative treatment environment, advocating for merging oncologists and cardiologists in a coordinated endeavor to maximize patient outcomes. In addition to clinical factors, the review explores the critical domain of patient education and support, acknowledging its crucial role in promoting informed decision-making and improving overall patient well-being. The latter portions of the text anticipate and consider upcoming treatments and existing research efforts that offer the potential for the future of cardio-oncology. This review seeks to provide a detailed viewpoint on the intricate connection between cancer treatments and cardiovascular well-being. Its objective is to encourage a more profound comprehension of the subject and prompt careful contemplation regarding the comprehensive care of cancer patients who confront the intricate difficulties presented by their treatment plans.

Indexed as

cancer therapiescardio-oncologycardiovascularheartrare cancers

Identifiers

PMID38269231
PMCPMC10806352
OpenAlexW4390166209

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.