Evidence map›Paper›PMID 38275739›Full record

ArticleBiology2024

Inhibition of Hyperglycemia and Hyperlipidemia by Blocking Toll-like Receptor 4: Comparison of Wild-Type and Toll-like Receptor 4 Gene Knockout Mice on Obesity and Diabetes Modeling.

Xingyu Zhao, Jiawei Zheng, Jing Wang, Bin Li, Wuyang Huang

Open access · goldAbstract read
In one paragraph

Article in Biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Xingyu ZhaoInstitute of Agro-Product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.ORCID 0000-0002-2596-5461
Jiawei ZhengSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
Jing WangCollege of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China.
Bin LiCollege of Food Science, Shenyang Agricultural University, Shenyang 110866, China.
Wuyang HuangInstitute of Agro-Product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.ORCID 0000-0002-3038-0636
Jiangsu University · CNNanjing Forestry University · CNShenyang Agricultural University · CN

Funding

Jiangsu Provincial Key Research and Development Program BE2021705
6 · The paper itself

Abstract

Innate immune receptor TLR4 plays an important role in glycolipid metabolism. The objective of this study is to investigate the inhibitory effects of blocking TLR4 on hyperglycemia and hyperlipidemia by comparing WT and TLR4

Indexed as

glycolipid metabolismknockoutobesity and diabetes modelingTLR4

Identifiers

PMID38275739
PMCPMC10813444
OpenAlexW4391098620

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.