SynthesisScience advances2024
Genetic architecture of alcohol consumption identified by a genotype-stratified GWAS and impact on esophageal cancer risk in Japanese people.
Open access · goldAbstract readMeta-Analysis
In one paragraph
Synthesis in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
9.8field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 23 citations in OpenAlex.
- Polymorphisms ADH1B rs1229984 and NAA25 rs4767364 correlate with head and neck cancer risk in Southern Punjab, Pakistan: a case-control study.Annals of medicine and surgery (2012) · 2026Article
- Genetic Risk, Healthy Lifestyle, and Risk Stratification for Diverticulitis.Journal of the American College of Surgeons · 2026Article
- Development of a triplex FMCA assay for genotyping three genes, ADH1B, ADH1C, and ALDH2, involved in alcohol metabolism.Scientific reports · 2026Article
- Integration of polygenic risk score with measured blood pressure reveals hidden risks of cardiovascular disease mortality: A Japanese prospective cohort study.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Article
- Meta-GWAS of Pig Semen Quality Traits Reveals Conserved Genes Regulating Mammalian Fertility.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Shared genetic architecture of psychoactive substance use and pan-cancer: insights from a large‑scale genome‑wide cross‑trait analysis.BMC medicine · 2026Article
- Genotype subtyping approach to identify unnoticed variants in diseases from GWAS data.BioData mining · 2026Article
- Impact of aldehyde dehydrogenase 2 polymorphism on lipid profile alterations in alcohol-abstinent adolescents stratified by steatotic liver disease status.Environmental health and preventive medicine · 2026Article
- Differential Impact of BMI-Associated Genetic Variants on Breast Cancer Risk: Insights From Mediation Analysis.Cancer science · 2026Article
- Relationship between age-related hearing loss and alcohol consumption in a Japanese population.Scientific reports · 2025Article
- Low Alanine Aminotransferase Levels in Alcohol Consuming Male Subjects, Carriers of the Common ALDH2 Deficient Variant, ALDH2*2.Hepatology research : the official journal of the Japan Society of Hepatology · 2025Review
- Recent updates and future perspectives about ALDH1B1 as a potential anticancer target: a review.Journal of cancer research and clinical oncology · 2025Review
- Uncovering genetic mechanisms associated with harmful use of alcohol in admixed Latin Americans.BMC genomics · 2025Article
- The Burden of Esophageal Cancer in Five East Asian Countries From 1990 to 2021 and Its Prediction Until 2036: An Analysis of the Global Burden of Diseases Study 2021.Thoracic cancer · 2025Article
- Personalized prediction of esophageal cancer risk based on virtually generated alcohol data.Journal of translational medicine · 2025Article
- Leveraging genome-wide association studies to better understand the etiology of cancers.Cancer science · 2025Review
- Development and validation of a risk prediction model for distant metastasis in muscle-invasive bladder cancer: a retrospective study integrating SEER data with external validation cohort and biomarker analysis.Frontiers in oncology · 2025Article
- Interplay between host genetics and gut microbiome composition in the Japanese population.Frontiers in microbiomes · 2025Article
- Factors associated with acquiring exercise habits through health guidance for metabolic syndrome among middle-aged Japanese workers: A machine learning approach.Preventive medicine reports · 2024Article
Corrections and comments
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Authors and funding
51 authors at 20 institutions in 3 countries.
Yuriko N KoyanagiDivision of Cancer Epidemiology and Prevention, Department of Preventive Medicine, Aichi Cancer Center Research Institute, Nagoya, Japan.ORCID 0000-0002-5675-3429
Masahiro NakatochiPublic Health Informatics Unit, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.ORCID 0000-0002-1838-4837
Shinichi NambaDepartment of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.ORCID 0000-0002-7486-3146
Isao OzeDivision of Cancer Epidemiology and Prevention, Department of Preventive Medicine, Aichi Cancer Center Research Institute, Nagoya, Japan.ORCID 0000-0002-0762-1147
Hadrien CharvatFaculty of International Liberal Arts, Juntendo University, Tokyo, Japan.
Akira NaritaDepartment of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.ORCID 0000-0002-9076-0710
Takahisa KawaguchiCenter for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID 0000-0001-7781-7404
Hiroaki IkezakiDepartment of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan.ORCID 0000-0002-6677-6341
Asahi HishidaDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.ORCID 0000-0002-4867-0201
Megumi HaraDepartment of Preventive Medicine, Faculty of Medicine, Saga University, Saga, Japan.ORCID 0000-0002-8708-3237
Toshiro TakezakiDepartment of International Island and Community Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.ORCID 0000-0001-7822-909X
Teruhide KoyamaDepartment of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.ORCID 0000-0002-8161-368X
Yohko NakamuraCancer Prevention Center, Chiba Cancer Center Research Institute, Chiba, Japan.ORCID 0000-0002-3655-887X
Sadao SuzukiDepartment of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.ORCID 0000-0001-5988-4849
Sakurako Katsuura-KamanoDepartment of Preventive Medicine, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.ORCID 0000-0002-9582-674X
Kiyonori KurikiLaboratory of Public Health, Division of Nutritional Sciences, School of Food and Nutritional Sciences, University of Shizuoka, Shizuoka, Japan.ORCID 0000-0003-4301-6566
Yasuyuki NakamuraDepartment of Public Health, Shiga University of Medical Science, Otsu, Japan.
Kenji TakeuchiDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.ORCID 0000-0001-8769-8955
Atsushi HozawaDepartment of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.ORCID 0000-0002-8031-8523
Kengo KinoshitaDepartment of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.ORCID 0000-0003-3453-2171
Yoichi SutohDivision of Biomedical Information Analysis, Iwate Tohoku Medical Megabank Organization, Iwate Medical University, Iwate, Japan.ORCID 0000-0002-1607-9759
Kozo TannoDepartment of Hygiene and Preventive Medicine, School of Medicine, Iwate Medical University, Iwate, Japan.ORCID 0000-0002-1264-0684
Atsushi ShimizuDivision of Biomedical Information Analysis, Iwate Tohoku Medical Megabank Organization, Iwate Medical University, Iwate, Japan.ORCID 0000-0001-8307-2461
Hidemi ItoDivision of Cancer Information and Control, Department of Preventive Medicine, Aichi Cancer Center Research Institute, Nagoya, Japan.ORCID 0000-0002-8023-4581
Yumiko KasugaiDivision of Cancer Epidemiology and Prevention, Department of Preventive Medicine, Aichi Cancer Center Research Institute, Nagoya, Japan.ORCID 0000-0003-4764-4455
Yukino KawakatsuDivision of Cancer Epidemiology and Prevention, Department of Preventive Medicine, Aichi Cancer Center Research Institute, Nagoya, Japan.ORCID 0000-0002-1522-2082
Yukari TaniyamaDivision of Cancer Information and Control, Department of Preventive Medicine, Aichi Cancer Center Research Institute, Nagoya, Japan.ORCID 0000-0001-9590-1693
Masahiro TajikaDepartment of Endoscopy, Aichi Cancer Center Hospital, Nagoya, Japan.ORCID 0000-0002-3761-6971
Yasuhiro ShimizuDepartment of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya, Japan.
Etsuji SuzukiDepartment of Epidemiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Yasuyuki HosonoDepartment of Pharmacology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Issei ImotoAichi Cancer Center Research Institute, Nagoya, Japan.ORCID 0000-0002-4150-7938
Yasuharu TabaraCenter for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Meiko TakahashiCenter for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID 0000-0002-8344-5472
Kazuya SetohCenter for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
BioBank Japan ProjectInstitute of Medical Science, The University of Tokyo, Tokyo, Japan.
Koichi MatsudaDepartment of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan.ORCID 0000-0001-7292-2686
Shiori NakanoDivision of Epidemiology, National Cancer Center Institute for Cancer Control, Tokyo, Japan.ORCID 0000-0001-5762-850X
Atsushi GotoDivision of Epidemiology, National Cancer Center Institute for Cancer Control, Tokyo, Japan.ORCID 0000-0003-0669-654X
Ryoko KatagiriDivision of Cohort Research, National Cancer Center Institute for Cancer Control, Tokyo, Japan.ORCID 0000-0002-4867-2450
Taiki YamajiDivision of Epidemiology, National Cancer Center Institute for Cancer Control, Tokyo, Japan.ORCID 0000-0002-4799-8782
Norie SawadaDivision of Cohort Research, National Cancer Center Institute for Cancer Control, Tokyo, Japan.ORCID 0000-0002-9936-1476
Shoichiro TsuganeDivision of Cohort Research, National Cancer Center Institute for Cancer Control, Tokyo, Japan.ORCID 0000-0003-4105-2774
Kenji WakaiDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Masayuki YamamotoDepartment of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.ORCID 0000-0002-9073-9436
Makoto SasakiDivision of Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical University, Iwate, Japan.ORCID 0000-0002-3108-4361
Fumihiko MatsudaCenter for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID 0000-0003-4557-4553
Yukinori OkadaDepartment of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.ORCID 0000-0002-0311-8472
Motoki IwasakiDivision of Epidemiology, National Cancer Center Institute for Cancer Control, Tokyo, Japan.ORCID 0000-0003-3319-4131
Paul BrennanGenomic Epidemiology Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0002-0518-8714
Keitaro MatsuoDivision of Cancer Epidemiology and Prevention, Department of Preventive Medicine, Aichi Cancer Center Research Institute, Nagoya, Japan.ORCID 0000-0003-1761-6314
Aichi Cancer Center · JPIwate Medical University · JPKyoto University · JPTohoku University · JPNational Institute of Infectious Diseases · JPNagoya University · JPShiga University of Medical Science · JPThe University of Tokyo · JPCentre international de recherche sur le cancer · FRHarvard University · USJuntendo University · JPKagoshima University · JPKyoto Prefectural University of Medicine · JPKyushu University · JPNagoya City University · JPOkayama University · JPRIKEN Center for Integrative Medical Sciences · JPSaga University · JPThe University of Osaka · JPTokushima University · JP
Funding
World Health Organization 001
Abstract
An East Asian-specific variant on
Indexed as
East Asian PeopleEsophageal NeoplasmsGenome-Wide Association StudyAlcohol DrinkingAldehyde Dehydrogenase, MitochondrialGenetic Predisposition to DiseaseGenotypeHumansPolymorphism, Single NucleotideAldehyde Dehydrogenase, MitochondrialALDH2 protein, human
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.