Evidence map›Paper›PMID 38280152›Full record

ArticleBiochemical genetics2024

Transcriptome Sequencing and Mass Spectrometry Reveal Genes Involved in the Non-mendelian Inheritance-Mediated Feather Growth Rate in Chicken.

Mohan Qiu, Zengrong Zhang, Shiliang Zhu, Siyang Liu, Han Peng, Xia Xiong, Jialei Chen, Chenming Hu, Li Yang, Xiaoyan Song and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemical genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Mohan Qiu *Animal Breeding and Genetics Key Laboratory of Sichuan Province, Sichuan Animal Science Academy, 7# Niusha Road, Chengdu, 610066, Sichuan, China.
Zengrong Zhang *Animal Breeding and Genetics Key Laboratory of Sichuan Province, Sichuan Animal Science Academy, 7# Niusha Road, Chengdu, 610066, Sichuan, China.
Shiliang ZhuAnimal Breeding and Genetics Key Laboratory of Sichuan Province, Sichuan Animal Science Academy, 7# Niusha Road, Chengdu, 610066, Sichuan, China.
Siyang LiuAnimal Breeding and Genetics Key Laboratory of Sichuan Province, Sichuan Animal Science Academy, 7# Niusha Road, Chengdu, 610066, Sichuan, China.
Han PengAnimal Breeding and Genetics Key Laboratory of Sichuan Province, Sichuan Animal Science Academy, 7# Niusha Road, Chengdu, 610066, Sichuan, China.
Xia XiongAnimal Breeding and Genetics Key Laboratory of Sichuan Province, Sichuan Animal Science Academy, 7# Niusha Road, Chengdu, 610066, Sichuan, China.
Jialei ChenAnimal Breeding and Genetics Key Laboratory of Sichuan Province, Sichuan Animal Science Academy, 7# Niusha Road, Chengdu, 610066, Sichuan, China.
Chenming HuAnimal Breeding and Genetics Key Laboratory of Sichuan Province, Sichuan Animal Science Academy, 7# Niusha Road, Chengdu, 610066, Sichuan, China.
Li YangAnimal Breeding and Genetics Key Laboratory of Sichuan Province, Sichuan Animal Science Academy, 7# Niusha Road, Chengdu, 610066, Sichuan, China.
Xiaoyan SongAnimal Breeding and Genetics Key Laboratory of Sichuan Province, Sichuan Animal Science Academy, 7# Niusha Road, Chengdu, 610066, Sichuan, China.
Bo XiaAnimal Breeding and Genetics Key Laboratory of Sichuan Province, Sichuan Animal Science Academy, 7# Niusha Road, Chengdu, 610066, Sichuan, China.
Chunlin YuAnimal Breeding and Genetics Key Laboratory of Sichuan Province, Sichuan Animal Science Academy, 7# Niusha Road, Chengdu, 610066, Sichuan, China. yuchunlin1984@163.com.
Chaowu YangAnimal Breeding and Genetics Key Laboratory of Sichuan Province, Sichuan Animal Science Academy, 7# Niusha Road, Chengdu, 610066, Sichuan, China. chaowuyang@163.com.
Sichuan Animal Science Academy · CN

Funding

Sichuan Province Basic Scientific Research Project SASA202101
6 · The paper itself

Abstract

The feather growth rate in chickens included early and late feathering. We attempted to characterize the genes and pathways associated with the feather growth rate in chickens that are not in agreement with Mendelian inheritance. Gene expression profiles in the hair follicle tissues of late-feathering cocks (LC), early-feathering cocks (EC), late-feathering hens (LH), and early-feathering hens (EH) were acquired using RNA sequencing (RNA-seq), mass spectrometry (MS), and quantitative reverse transcription PCR (qRT‑PCR). A total of 188 differentially expressed genes (DEGs) were ascertained in EC vs. LC and 538 DEGs were identified in EH vs. LH. We observed that 14 up-regulated genes and 9 down-regulated genes were screened both in EC vs. LC and EH vs. LH. MS revealed that 41 and 138 differentially expressed proteins (DEPs) were screened out in EC vs. LC and EH vs. LH, respectively. Moreover, these DEGs and DEPs were enriched in multiple feather-related pathways, including JAK-STAT, MAPK, WNT, TGF-β, and calcium signaling pathways. qRT-PCR assay showed that the expression of WNT8A was decreased in LC compared with EC, while ALK and GRM4 expression were significantly up-regulated in EH relative to LH. This study helps to elucidate the potential mechanism of the feather growth rate in chickens that do not conform to genetic law.

Indexed as

ChickensFeathersTranscriptomeAnimalsAvian ProteinsFemaleGene Expression ProfilingMass SpectrometrySequence Analysis, RNAAvian ProteinsChickenDifferentially expressed genesFeather growth rateMass spectrometryRNA sequencing

Identifiers

PMID38280152
PMCPMC11427531
OpenAlexW4391275304

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.