ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2024
A Gender-, Age-, and Weight Status-Specific Analysis of the High Prevalence of Hyperuricemia Among Chinese Children and Adolescents with Obesity.
Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed.
- Associations between multiple essential trace metal concentrations and risk of hyperuricemia: insights from a central Chinese population.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Article
- From Multidimensional Management to Mechanistic Insight: A Review of Interventions for Hyperuricemia.International journal of molecular sciences · 2026Review
- The relationship between secondhand smoke exposure in Chinese children and adolescents and renal function and hyperuricemia: a cross-sectional study.Frontiers in pediatrics · 2026Article
- Traditional Chinese medicine constitution types and apolipoprotein B in hyperuricemia: Associations with cardiovascular risk.Journal of medical biochemistry · 2025Article
- Clinical and dietary risk factors of hyperuricemia in Korean children and adolescents: the 8th Korea National Health and Nutrition Examination Survey.Kidney research and clinical practice · 2025Article
- Excess Weight Loss at 6 Months Following Laparoscopic Sleeve Gastrectomy Correlates with the Remission of Hyperuricemia.Obesity surgery · 2025Article
- Correlation Analysis between Serum Uric Acid Levels and Bone Mineral Density in Children with Obesity.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Triponderal mass index can be used as a potential tool to predict the risk of hyperuricemia in children and adolescents with obesity: a population-based study.Frontiers in nutrition · 2025Article
- Aloe-emodin attenuates hyperuricemia-induced renal injury in mice by mitigating inflammation and oxidative stress.Frontiers in nutrition · 2025Article
- A 6-year-old girl with gout: a case report and another unusual presentation.Translational pediatrics · 2024Article
- The Effects of Parental Food Education on Children's Food Literacy: The Mediating Role of Parent-Child Relationship and Learning Motivation.Nutrients · 2024Article
- Association between serum uric acid-to-high-density lipoprotein cholesterol ratio and metabolic dysfunction-associated steatotic liver disease among Chinese children with obesity.Frontiers in endocrinology · 2024Article
- Ensemble machine learning prediction of hyperuricemia based on a prospective health checkup population.Frontiers in physiology · 2024Article
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10 authors.
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Abstract
Objective: To explore the gender-, age-, and weight status-specific prevalence of hyperuricemia (HUA) and its associated risk factors among Chinese children and adolescents with obesity. Methods: A total of 1329 children aged 2-17 years, who were diagnosed with obesity and hospitalized in our center from January 2016 to December 2022 were recruited. They were divided into mild obesity, moderate obesity, and severe obesity groups. HUA was defined as fasting serum uric acid level >420 μmol/L for boys and >360 μmol/L for girls. Multivariate logistic regression analyses were performed to identify risk factors for HUA. Results: The highest proportion of hospitalized obese children was aged 10-13 years comprising 677 (50.9%) followed by those aged 6-9 years comprising 348 (26.2%) whereas the least proportion was aged 2-5 years comprising 76 (5.7%). The above differences in age distribution were still present in subgroup analyses according to weight status. Most hospitalized obese children were boys (64.7%), especially in the severe obesity group (75.0%). The overall estimated prevalence of HUA in obese children was 54.8%. It presented a gradual increase trend over the last 7 years, with more rapidly in boys than in girls. Subgroup analysis by weight status showed that the prevalence of HUA was higher in children with moderate obesity (64.3%) and severe obesity (64.2%) when compared with mild obesity (48.2%) ( Conclusion: The prevalence of HUA in Chinese obese children and adolescents is unexpectedly high. Childhood HUA was significantly associated with obesity. Gender and age differences were observed in the association between childhood obesity and HUA. Obese children aged ≥12 years should be focused on screening the risk of HUA.
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