Evidence map›Paper›PMID 38289659›Full record

ArticleeLife2024

Orai-mediated calcium entry determines activity of central dopaminergic neurons by regulation of gene expression.

Rishav Mitra, Shlesha Richhariya, Gaiti Hasan

Open access · goldAbstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Gene expression regulation by CaCellular & molecular biology letters · 2026
    Pooled it
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  3. Review
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Rishav MitraNational Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, India.ORCID https://orcid.org/0000-0001-6840-6160
Shlesha RichhariyaNational Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, India.
Gaiti HasanNational Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, India.ORCID https://orcid.org/0000-0001-7194-383X
Tata Institute of Fundamental Research · IN

Funding

Department of Biotechnology, Ministry of Science and Technology, India BT/PR28450/MED/122/2018
6 · The paper itself

Abstract

Maturation and fine-tuning of neural circuits frequently require neuromodulatory signals that set the excitability threshold, neuronal connectivity, and synaptic strength. Here, we present a mechanistic study of how neuromodulator-stimulated intracellular Ca

Indexed as

CalciumDopaminergic NeuronsCalcium, DietaryCholinergic AgentsDopamineHistone-Lysine N-MethyltransferaseCalciumCalcium, DietaryCholinergic AgentsDopamineHistone-Lysine N-MethyltransferaseD. melanogasterDrosophila flightgeneticsgenomicshistone modificationsneuromodulationneurosciencePPL1 DANsSOCEtrithorax-like/GAF

Identifiers

PMID38289659
PMCPMC10945566
OpenAlexW4385220997

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.